Butyl Alcohol

Butyl Alcohol

SCHEMBL7624032

CCCCO.CCCC[O-].[K+]

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA

The experimentally established mechanism targets of Butyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.65
SMN1; SMN2 Q16637 1/20 0.53
LMNA P02545 4/20 0.50
TSHR P16473 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
HSD17B10 Q99714 1/20 0.50
CES2 O00748 2/20 0.35
CES1 P23141 2/20 0.35
THRB P10828 1/20 0.32
HTT P42858 1/20 0.32
DNM1 Q05193 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyl Alcohol SCHEMBL6030420 0.94 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2LMNATSHRMEN1
Butyl Alcohol SCHEMBL3046184 0.94 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2LMNATSHRMEN1
Butyl Alcohol SCHEMBL7693245 0.94 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2LMNATSHRMEN1
Butyl Alcohol SCHEMBL1501462 0.94 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2LMNATSHRMEN1
Butyl Alcohol SCHEMBL8509052 0.92 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2LMNATSHRMEN1
Butyl Alcohol SCHEMBL29968488 0.92 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2LMNATSHRMEN1
Propanol SCHEMBL28311045 0.85 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2LMNATSHRMEN1
Ethylene Glycol SCHEMBL27490784 0.85 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2LMNATSHRMEN1
Butyl Alcohol SCHEMBL8815824 0.85 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2LMNATSHRMEN1
Potassium Ion SCHEMBL17113317 0.84 TSHR (0.46) ALDH1A1SMN1; SMN2LMNATSHRCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1223941-A2 THERAPEUTIC TREATMENTS COMPRISING ADMINISTRATOIN OF CERTAIN STEROIDS FOR BLOOD CELL DEFICIENCIES Hollis-Eden Pharmaceuticals Inc. (US) 2002-07-24 EP disclosed
EP-1163256-A1 HEMIHYDRATE OF 16.ALPHA.-BROMOEPIANDROSTERONE Hollis-Eden Pharmaceuticals Inc. (US) 2001-12-19 EP disclosed
WO-2001030802-A2 THERAPEUTIC TREATMENTS COMPRISING ADMINISTRATION OF CERTAIN STEROIDS FOR BLOOD CELL DEFICIENCIES HOLLIS-EDEN PHARMACEUTICALS, INC. (US) 2001-05-03 WO disclosed
WO-2000056757-A1 IMMUNOMODULATORY STEROIDS, IN PARTICULAR THE HEMIHYDRATE OF 16.ALPHA.-BROMOEPIANDROSTERONE HOLLIS-EDEN PHARMACEUTICALS, INC. (US) 2000-09-28 WO disclosed