Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.33 |
| ▸ | MPO | P05164 | 4/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7625592 | 0.89 | TBXAS1 (0.45) | CAPN1TBXAS1MPO | |
| SCHEMBL7616768 | 0.76 | TBXAS1 (0.54) | TBXAS1 | |
| SCHEMBL7621773 | 0.75 | TBXAS1 (0.61) | TBXAS1 | |
| SCHEMBL7614088 | 0.75 | TBXAS1 (0.61) | TBXAS1 | |
| SCHEMBL7616487 | 0.73 | ALDH1A1 (0.41) | — | |
| SCHEMBL2787115 | 0.72 | TBXAS1 (0.57) | CAPN1TBXAS1 | |
| SCHEMBL7618079 | 0.70 | TBXAS1 (0.41) | TBXAS1MPO | |
| SCHEMBL7620248 | 0.70 | HPGD (0.43) | TBXAS1 | |
| SCHEMBL7613936 | 0.69 | CYP3A4 (0.45) | TBXAS1 | |
| SCHEMBL7626543 | 0.68 | TBXAS1 (0.33) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232166-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | Pharmasset Limited (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034618-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | PHARMASSET LIMITED (US) | 2001-05-17 | — | — | WO | disclosed |