Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | TSPO | P30536 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 6/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7626419 | 0.94 | TSPO (0.58) | MAPTTSPOTP53ADORA1ALDH1A1 | |
| SCHEMBL7631555 | 0.91 | TSPO (0.65) | MAPTTSPOADORA1KDM4EALDH1A1 | |
| SCHEMBL7632526 | 0.90 | TSPO (0.54) | MAPTTSPOTP53ADORA1POLB | |
| SCHEMBL7002472 | 0.88 | TSPO (0.56) | MAPTTSPOTP53GAAPOLB | |
| SCHEMBL7005121 | 0.87 | MAPT (0.60) | MAPTTSPOTP53GAAPOLB | |
| SCHEMBL7001447 | 0.80 | TSPO (0.62) | MAPTTSPOTP53POLBKDM4E | |
| SCHEMBL5702445 | 0.78 | TSPO (0.67) | MAPTTSPOTP53POLB | |
| SCHEMBL7626011 | 0.78 | TSPO (0.64) | MAPTTSPOTP53 | |
| SCHEMBL7001998 | 0.76 | TSPO (0.57) | MAPTTSPOTP53POLBKDM4E | |
| SCHEMBL3922114 | 0.75 | KMT2A (0.46) | MAPTTSPOADORA1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451795-B1 | CENTRAL NEURODEGENERATIVE DISEASES | SANOFI-SYNTHELABO (FR) | 2002-09-17 | — | — | US | disclosed |