Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6514548 | 0.83 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1MAPTLMNAHPGD | |
| SCHEMBL17433924 | 0.82 | EEF2K (0.45) | ALDH1A1MAPTPOLBLMNAGAA | |
| SCHEMBL7145632 | 0.80 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1MAPTPOLBLMNA | |
| SCHEMBL17433912 | 0.77 | EEF2K (0.41) | ALDH1A1L3MBTL1CYP2C9CYP2C19KDM4E | |
| SCHEMBL17434268 | 0.76 | PDE5A (0.39) | ALDH1A1L3MBTL1LMNATP53HPGD | |
| SCHEMBL17434340 | 0.75 | KMT2A (0.58) | ALDH1A1L3MBTL1MAPTLMNAHPGD | |
| SCHEMBL12410746 | 0.74 | CYP2C19 (0.43) | ALDH1A1MAPTPOLBCYP2C9CYP2C19 | |
| SCHEMBL11875375 | 0.72 | KMT2A (0.55) | MAPTPOLBHPGDCYP2C9CYP2C19 | |
| SCHEMBL2201841 | 0.70 | CA12 (0.54) | ALDH1A1MAPTLMNAGAAHPGD | |
| SCHEMBL18193667 | 0.70 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1LMNATP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | ANDRIANJARA CHARLES (FR) | 2002-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | MMP13, MMP9, MMP3 | ALDH1A1 1357/4885L3MBTL1 4265/4885MAPT 4823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.