SCHEMBL7628154

SCHEMBL7628154

c1ccc([Si](=N[Si](c2ccccc2)(c2ccccc2)c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7631463 0.68
SCHEMBL146838 0.68 ESR1 (0.40) ESR1ESR2
SCHEMBL49918 0.64 ESR1 (0.42) ESR1ESR2
SCHEMBL1416688 0.62 ESR1 (0.36) ESR1ESR2
SCHEMBL49706 0.62 ALDH1A1 (0.43) ESR1ESR2
SCHEMBL3275968 0.59 ESR1 (0.33) ESR1ESR2
SCHEMBL2786417 0.59 ESR1 (0.33) ESR1ESR2
SCHEMBL8762334 0.59 MIF (0.42) ESR1ESR2
SCHEMBL873949 0.58 RAB9A (0.36) ESR1ESR2
SCHEMBL15949904 0.57 DUT (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6455458-B1 HIGH MOLECULAR WEIGHT POLYOLEFIN; GROUP 4 TRANSITION METAL COMPLEXES HAVING A BIDENTATE ANCILLARY LIGAND SYSTEM OF ONE CYCLOPENTADIENYL GROUP BOUND TO THE TRANSITION METAL AND A GROUP 15 OR GROUP 16 ATOM COVALENTLY BOUND THROUGH A BRIDGING EXXONMOBIL CHEMICAL PATENTS INC. 2002-09-24 US disclosed
EP-1097161-A1 TETHERED MONOCYCLOPENTADIENYL POLYMERIZATION CATALYSTS EXXON CHEMICAL PATENTS INC. (US) 2001-05-09 EP disclosed
WO-2000002891-A1 TETHERED MONOCYCLOPENTADIENYL POLYMERIZATION CATALYSTS EXXON CHEMICAL PATENTS INC. (US) 2000-01-20 WO disclosed