Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7631332 | 0.79 | MTNR1A (0.42) | MTNR1AMTNR1B | |
| SCHEMBL7627899 | 0.79 | MTNR1A (0.43) | MTNR1AMTNR1B | |
| SCHEMBL10750642 | 0.74 | SMN1; SMN2 (0.46) | MTNR1AMTNR1B | |
| SCHEMBL7627993 | 0.70 | TDP1 (0.52) | MTNR1AMTNR1B | |
| SCHEMBL7636053 | 0.69 | PGR (0.35) | PGR | |
| SCHEMBL9727669 | 0.68 | MTNR1A (0.43) | MTNR1AMTNR1B | |
| SCHEMBL7630325 | 0.67 | SIRT2 (0.42) | MTNR1AMTNR1BSIRT2 | |
| SCHEMBL5502112 | 0.67 | DRD2 (0.45) | SIRT2 | |
| SCHEMBL7626493 | 0.66 | MTNR1A (0.49) | MTNR1AMTNR1BSIRT2 | |
| SCHEMBL14435037 | 0.65 | CYP3A4 (0.49) | SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888327-B1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | MENARINI LAB (ES) | 2002-06-12 | — | — | EP | disclosed |
| US-5990142-A | ANTIINFLAMMATORY AGENTS AND ANTIALLERGENS HAVING GOOD ORAL ADSORPTION AND BIOAVAILABILITY; CARDIOTONIC AND ANTIISCHEMIC AGENTS | LABORATORIOS MENARINI S.A. (ES) | 1999-11-23 | — | — | US | disclosed |
| EP-0888327-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034885-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-09-25 | — | — | WO | disclosed |