Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435039 | 0.93 | AKR1B1 (0.40) | MTNR1AMTNR1B | |
| SCHEMBL5506271 | 0.89 | MAOA (0.41) | — | |
| SCHEMBL5505040 | 0.84 | AKR1B1 (0.37) | — | |
| SCHEMBL9727677 | 0.82 | PTGDR2 (0.38) | — | |
| SCHEMBL9727764 | 0.81 | IGF1R (0.35) | — | |
| SCHEMBL9727674 | 0.79 | LTB4R (0.38) | — | |
| SCHEMBL5502112 | 0.78 | DRD2 (0.45) | — | |
| SCHEMBL10655255 | 0.77 | ALOX5 (0.42) | — | |
| SCHEMBL9727749 | 0.77 | MAOA (0.34) | — | |
| SCHEMBL14435033 | 0.76 | HTR6 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091533-A | Treating allergies, cardiovascular disorders, inflammation | MERCK FROSST CANADA, INC. (CA) | 1992-02-25 | — | — | US | disclosed |
| EP-0447189-A1 | 5-Hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors | MERCK FROSST CANADA INC. (CA) | 1991-09-18 | — | — | EP | disclosed |