Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.65 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.65 |
| ▸ | CCR2 | P41597 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 2/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | RHOC | P08134 | 1/20 | 0.47 |
| ▸ | RHOA | P61586 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 2/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.46 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532778 | 0.91 | SLC20A2 (0.54) | SLC20A2SLC20A1CCR2KDM1AMEN1 | |
| SCHEMBL7537253 | 0.90 | IDH2 (0.54) | SLC20A2SLC20A1CCR2MEN1KMT2A | |
| SCHEMBL7531807 | 0.88 | SLC20A2 (0.53) | SLC20A2SLC20A1CCR2S1PR2MEN1 | |
| SCHEMBL7531650 | 0.87 | ACLY (0.55) | SLC20A2SLC20A1MEN1KMT2ARAB9A | |
| SCHEMBL7562743 | 0.86 | ACLY (0.52) | SLC20A2SLC20A1CCR2S1PR2MEN1 | |
| SCHEMBL7533744 | 0.85 | SLC20A2 (0.58) | SLC20A2SLC20A1CCR2MEN1KMT2A | |
| SCHEMBL7538051 | 0.84 | HTT (0.49) | SLC20A2SLC20A1CCR2MEN1KMT2A | |
| SCHEMBL7539025 | 0.84 | MEN1 (0.62) | MEN1KMT2ARAB9AACLYAVPR2 | |
| SCHEMBL7539041 | 0.83 | MEN1 (0.53) | S1PR2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7120286 | 0.82 | SLC20A2 (0.74) | SLC20A2SLC20A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |