Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 5/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324968 | 0.80 | ALDH1A1 (0.45) | LMNAIDO1HTTALDH1A1 | |
| SCHEMBL1537132 | 0.74 | ALDH1A1 (0.45) | LMNACA2CAMK2ACALM1ESR1 | |
| SCHEMBL112488 | 0.74 | CYP4F2 (0.66) | LMNACA2CAMK2AESR1ESR2 | |
| SCHEMBL18324623 | 0.74 | CA2 (0.45) | LMNACA2CAMK2ACALM1ESR1 | |
| SCHEMBL10780331 | 0.74 | CA2 (0.54) | LMNACA2CAMK2AESR1ESR2 | |
| SCHEMBL11835825 | 0.74 | MAPT (0.33) | HTTALDH1A1PKMTDP1 | |
| SCHEMBL9364458 | 0.74 | PTGS1 (0.42) | LMNAIDO1ALDH1A1PKMTDP1 | |
| SCHEMBL1808493 | 0.74 | CA2 (0.54) | CA2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL15663073 | 0.72 | CA2 (0.43) | LMNACA2CAMK2ACALM1ESR1 | |
| SCHEMBL7646563 | 0.72 | CYP4F2 (0.63) | LMNACA2CAMK2AESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350892-B1 | ENZYME INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2002-02-26 | — | — | US | disclosed |