Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7367260 | 0.82 | CES2 (0.47) | ALDH1A1HPGDLMNAKDM4ECES2 | |
| SCHEMBL7632091 | 0.80 | LMNA (0.49) | ALDH1A1LMNAHTTIDO1 | |
| SCHEMBL9458372 | 0.79 | L3MBTL1 (0.50) | ALDH1A1HPGDLMNAKDM4ECES2 | |
| SCHEMBL3251246 | 0.78 | ALDH1A1 (0.44) | ALDH1A1LMNACES2CES1AKR1B1 | |
| SCHEMBL27791495 | 0.77 | TSHR (0.61) | ALOX12LMNACES2CES1AKR1B1 | |
| SCHEMBL29185461 | 0.77 | CA12 (0.41) | ALDH1A1ALOX12LMNACES2CES1 | |
| SCHEMBL9755852 | 0.77 | IDO1 (0.43) | ALDH1A1HPGDALOX12LMNACES2 | |
| SCHEMBL2154441 | 0.76 | CES1 (0.48) | ALDH1A1LMNAKDM4ECES2CES1 | |
| SCHEMBL6295378 | 0.76 | CES2 (0.48) | ALDH1A1LMNAKDM4ECES2CES1 | |
| SCHEMBL3048337 | 0.76 | ALDH1A1 (0.59) | ALDH1A1LMNACES2CES1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691959-B1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |
| EP-0825184-A1 | Heterocyclic derivatives as platelet aggregation inhibitors | ZENECA LIMITED (GB) | 1998-02-25 | — | — | EP | disclosed |
| EP-0641207-A4 | ENANTIOMERIC CYNEMICIN ANALOGS, PREPARATION AND USE THEREOF. | SCRIPPS RESEARCH INST (US) | 1996-08-14 | — | — | EP | disclosed |
| EP-0691959-A1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-17 | — | — | EP | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| EP-0641207-A1 | ENANTIOMERIC CYNEMICIN ANALOGS, PREPARATION AND USE THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 1995-03-08 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |
| WO-1994022834-A1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |
| US-5281710-A | Antibiotics or antitumor agents | THE SCRIPPS RESEARCH INSTITUTE (US) | 1994-01-25 | — | — | US | disclosed |
| WO-1993023046-A1 | ENANTIOMERIC CYNEMICIN ANALOGS, PREPARATION AND USE THEREOF | THE SCRIPPS RESEARCH INSTITUTE (US) | 1993-11-25 | — | — | WO | disclosed |
| US-4980485-A | Method of manufacturing optically-active periplanone-b | JAPAN TOBACCO INC. (JP) | 1990-12-25 | — | — | US | disclosed |
| US-4755626-A | 4-isopropyl-7-methylene-5-cyclodecen-1-ol | JAPAN TOBACCO, INC. (JP) | 1988-07-05 | — | — | US | disclosed |
| US-4710581-A | Nucleophilic substitution process | ETHYL CORPORATION (US) | 1987-12-01 | — | — | US | disclosed |
| US-4581463-A | Nucleophilic substitution process combined with additional reaction steps | ETHYL CORPORATION (US) | 1986-04-08 | — | — | US | disclosed |
| US-RE29882-E | SALT FORMATION, REARRANGEMENT, DESULFURIZATION | OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1979-01-16 | — | — | US | disclosed |
| US-4056569-A | Ortho-[(alkylthio)(aminocarbonyl)methyl]anilines | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1977-11-01 | — | — | US | disclosed |
| US-3996264-A | Synthesis of oxindoles from anilines and intermediates therein | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1976-12-07 | — | — | US | disclosed |
| US-3972894-A | Synthesis of oxindoles from anilines and β-thio carboxylic esters or amides | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1976-08-03 | — | — | US | disclosed |