Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7636442 | 0.87 | — | — | |
| SCHEMBL7632013 | 0.81 | DRD2 (0.34) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7635112 | 0.79 | RAB9A (0.35) | — | |
| SCHEMBL7632175 | 0.78 | IDO1 (0.31) | GABRA1GABRA5 | |
| SCHEMBL7628649 | 0.77 | TSHR (0.38) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL7634542 | 0.69 | MAPT (0.52) | — | |
| SCHEMBL9257154 | 0.67 | KMT2A (0.33) | — | |
| SCHEMBL7627221 | 0.67 | DRD2 (0.33) | — | |
| SCHEMBL7624761 | 0.66 | MAPT (0.43) | — | |
| SCHEMBL10584058 | 0.62 | ACHE (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975573-B1 | TRISUBSTITUTED PHENYL DERIVATIVES HAVING RETINOID AGONIST, ANTAGONIST OR INVERSE AGONIST TYPE BIOLOGICAL ACTIVITY | ALLERGAN SALES INC (US) | 2002-09-18 | — | — | EP | disclosed |