Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7636442 | 0.80 | — | — | |
| SCHEMBL7632092 | 0.79 | GABRA1 (0.31) | — | |
| SCHEMBL3125917 | 0.75 | KDM4E (0.56) | L3MBTL1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10385495 | 0.74 | LMNA (0.41) | L3MBTL1MAPTALDH1A1MAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL10385497 | 0.74 | KDM4E (0.55) | L3MBTL1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5074488 | 0.71 | CA1 (0.42) | MAPTSMN1; SMN2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL10584058 | 0.69 | ACHE (0.37) | RAB9AL3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL18304615 | 0.69 | ENPP2 (0.46) | MAPTMEN1KMT2ACYP3A4CYP1A2 | |
| SCHEMBL16417118 | 0.68 | CYP1A2 (0.56) | MAPTALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6585052 | 0.68 | MEN1 (0.40) | RAB9AL3MBTL1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975573-B1 | TRISUBSTITUTED PHENYL DERIVATIVES HAVING RETINOID AGONIST, ANTAGONIST OR INVERSE AGONIST TYPE BIOLOGICAL ACTIVITY | ALLERGAN SALES INC (US) | 2002-09-18 | — | — | EP | disclosed |