Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD1 | P21728 | 3/20 | 0.41 |
| ▸ | DRD5 | P21918 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218359 | 0.80 | KDM4E (0.37) | ALDH1A1CYP1A2CYP3A4CYP2C9ALOX15 | |
| SCHEMBL4581239 | 0.78 | METAP1 (0.63) | METAP1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30777630 | 0.78 | METAP1 (0.63) | METAP1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL17108416 | 0.70 | MPO (0.59) | METAP1ALDH1A1CYP1A2ADORA1CYP19A1 | |
| SCHEMBL29633762 | 0.70 | DRD1 (0.58) | METAP1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2914928 | 0.70 | DRD1 (0.58) | METAP1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL15869786 | 0.70 | METAP1 (0.54) | METAP1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23835146 | 0.70 | METAP1 (0.73) | METAP1ALDH1A1DRD2DRD1DRD5 | |
| SCHEMBL30887372 | 0.70 | METAP1 (0.73) | METAP1ALDH1A1DRD2DRD1DRD5 | |
| SCHEMBL6907774 | 0.68 | DRD1 (0.68) | METAP1CYP3A4DRD2DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627247-A | COMPOUNDS OF CYCLOPENTADIENE OR INDENE WITH FLUORENE AND GROUP IV METALS | PHILLIPS PETROLEUM COMPANY (US) | 1997-05-06 | — | — | US | claimed |
| WO-2019188644-A1 | TRANSITION METAL COMPOUND, CATALYST FOR OLEFIN POLYMERIZATION AND METHOD FOR PRODUCING OLEFIN POLYMER | 三井化学株式会社 | 2019-10-03 | — | — | WO | disclosed |
| EP-0849288-B1 | Catalyst for polymerization of an olefin, and method for producing an olefin polymer | TOSOH CORP (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-5906955-A | Catalyst for polymerization of an olefin, and method for producing an olefin polymer | TOSOH CORPORATION (JP) | 1999-05-25 | — | — | US | disclosed |
| EP-0849288-A1 | Catalyst for polymerization of an olefin, and method for producing an olefin polymer | TOSOH CORPORATION (JP) | 1998-06-24 | — | — | EP | disclosed |