SCHEMBL218359

SCHEMBL218359

COc1[c]c2c(cc1)-c1ccccc1C2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.37
MAPT P10636 6/20 0.37
ALDH1A1 P00352 5/20 0.37
SMN1; SMN2 Q16637 4/20 0.37
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
RAB9A P51151 3/20 0.37
NPC1 O15118 2/20 0.37
HPGD P15428 3/20 0.37
LMNA P02545 2/20 0.37
MAPK1 P28482 2/20 0.35
PTGS2 P35354 2/20 0.35
MAOA P21397 2/20 0.34
GAA P10253 3/20 0.34
CASP3 P42574 2/20 0.34
SENP8 Q96LD8 2/20 0.34
SENP7 Q9BQF6 2/20 0.34
SENP6 Q9GZR1 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CASP6 P55212 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL217121 0.82 ALDH1A1 (0.34) KDM4EMAPTALDH1A1SMN1; SMN2RAB9A
SCHEMBL4921196 0.82 MEN1 (0.38) KDM4EMAPTALDH1A1SMN1; SMN2MEN1
SCHEMBL7633764 0.80 METAP1 (0.47) ALDH1A1MAOACYP1A2HTR2CCYP3A4
SCHEMBL328868 0.80 MAPT (0.35) KDM4EMAPTALDH1A1SMN1; SMN2RAB9A
SCHEMBL4916055 0.80 NPC1 (0.35) KDM4EMAPTALDH1A1SMN1; SMN2MEN1
SCHEMBL4915519 0.79 LTA4H (0.35) KDM4EMAPTALDH1A1SMN1; SMN2MEN1
SCHEMBL4723228 0.78 PTGS2 (0.48) KDM4EMAPTALDH1A1SMN1; SMN2MEN1
SCHEMBL2478927 0.77 RAB9A (0.40) KDM4EMAPTALDH1A1SMN1; SMN2RAB9A
SCHEMBL216980 0.77 ALDH1A1 (0.40) KDM4EMAPTALDH1A1SMN1; SMN2MEN1
SCHEMBL1029280 0.74 ALDH1A1 (0.38) KDM4EMAPTALDH1A1SMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9296738-B2 Organic electroluminescent material, the process for preparing the same and OLED device using the same EVERDISPLAY OPTRONICS (SHANGHAI) LIMITED (CN) 2016-03-29 US claimed
US-20150203485-A1 ORGANIC ELECTROLUMINESCENT MATERIAL, THE PROCESS FOR PREPARING THE SAME AND OLED DEVICE USING THE SAME EVERDISPLAY OPTRONICS (SHANGHAI) CO., LTD. (CN) 2015-07-23 US claimed
EP-0577581-B1 Method for controlling the melting points and molecular weights of syndiotactic polyolefins using metallocene catalyst systems FINA TECHNOLOGY (US) 2000-07-05 EP claimed
EP-3438102-B1 GLYCIDYL ESTER COMPOUND PREPARATION METHOD KOLON INC (KR) 2021-07-07 EP disclosed
US-10954206-B2 Glycidyl ester compound preparation method KOLON INDUSTRIES, INC. (KR) 2021-03-23 US disclosed
US-20200299247-A1 GLYCIDYL ESTER COMPOUND PREPARATION METHOD KOLON INDUSTRIES, INC. (KR) 2020-09-24 US disclosed
EP-3495424-B1 COMPOSITION FOR PHOTO-ALIGNMENT LAYER AND PHOTO-ALIGNMENT LAYER LG CHEMICAL LTD (KR) 2020-09-09 EP disclosed
CN-107109231-B Vertically oriented layer comprising cyclic olefin (co) polymer 株式会社LG化学 2020-03-06 CN disclosed
US-10453420-B2 Base film, laminated structure including the same, and display device LG CHEM, LTD. (KR) 2019-10-22 US disclosed
EP-3495424-A1 COMPOSITION FOR PHOTO-ALIGNMENT LAYER AND PHOTO-ALIGNMENT LAYER LG Chem, Ltd. (KR) 2019-06-12 EP disclosed
EP-3196236-B1 VERTICAL ALIGNMENT FILM COMPRISING (CO)POLYMER OF CYCLIC OLEFIN COMPOUND LG CHEMICAL LTD (KR) 2019-04-10 EP disclosed
US-20080200475-A1 4-Piperazinothieno[2,3-D] Pyrimidine Compounds As Platelet Aggregation Inhibitors PFIZER INC. 2008-08-21 US disclosed
US-20070293640-A1 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2007-12-20 US disclosed
EP-1866317-A1 4-PIPERAZINOTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS Pharmacia & Upjohn Company LLC (US) 2007-12-19 EP disclosed
US-7294681-B2 Mutliple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-11-13 US disclosed
US-7223822-B2 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-29 US disclosed
WO-2006103555-A1 4-PIPERAZINOTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS PHARMACIA & UPJOHN COMPANY LLC (US) 2006-10-05 WO disclosed
EP-1473323-A1 Polyethylene composition and process for producing same Tosoh Corporation (JP) 2004-11-03 EP disclosed
US-20040214953-A1 Polyethylene composition and process for producing same TOSOH CORPORATION 2004-10-28 US disclosed
US-5688735-A COORDINATION CATALYST FINA TECHNOLOGY, INC. (US) 1997-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150203485-A1 ORGANIC ELECTROLUMINESCENT MATERIAL, THE PROCESS FOR PREPARING THE SAME AND OLED DEVICE USING THE SAME OCIAD1, OCIAD2, OR10J3 KDM4E 1407/4885MAPT 3498/4885ALDH1A1 897/4885
US-20200299247-A1 GLYCIDYL ESTER COMPOUND PREPARATION METHOD AGER, CYP4A11, GK KDM4E 645/4885MAPT 2759/4885ALDH1A1 2757/4885
US-10954206-B2 Glycidyl ester compound preparation method AGER, CYP4A11, GK KDM4E 645/4885MAPT 2759/4885ALDH1A1 2757/4885
US-20080200475-A1 4-Piperazinothieno[2,3-D] Pyrimidine Compounds As Platelet Aggregation Inhibitors PF4, TBXA2R, P2RY4 KDM4E 2775/4885MAPT 4568/4885ALDH1A1 849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.