SCHEMBL7633767

SCHEMBL7633767

COc1ccc2c(c1)[CH]c1cc(OC)ccc1-2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
CA7 P43166 3/20 0.48
CA9 Q16790 3/20 0.48
CA12 O43570 2/20 0.48
CA14 Q9ULX7 2/20 0.48
ALDH1A1 P00352 5/20 0.47
CYP1A2 P05177 4/20 0.47
MEN1 O00255 4/20 0.47
MAPT P10636 4/20 0.47
KMT2A Q03164 4/20 0.47
CYP3A4 P08684 3/20 0.47
CYP2D6 P10635 2/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2C19 P33261 2/20 0.47
HPGD P15428 1/20 0.47
RAB9A P51151 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
APP P05067 1/20 0.47
SNCA P37840 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8167266 0.89 GPR3 (0.50) CA1CA2CA7CA9CA12
SCHEMBL27692616 0.80 CA1 (0.48) CA1CA2CA7CA9CA12
SCHEMBL27745819 0.76 ABL1 (0.44) CA1CA2CA7CA9CA12
SCHEMBL8162709 0.76 CYP1A2 (0.47) ALDH1A1CYP1A2MEN1MAPTKMT2A
SCHEMBL346790 0.76 ALDH1A1 (0.64) CA1CA2CA7CA9CA12
SCHEMBL1134724 0.76 ALDH1A1 (0.64) CA1CA2CA7CA9CA12
SCHEMBL6046740 0.75 KIF11 (0.41) GPR3
SCHEMBL16510121 0.73 MEN1 (0.46) CA1CA2CA7CA9CA12
SCHEMBL12325065 0.72 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL12326180 0.72 CA1 (0.50) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5627247-A COMPOUNDS OF CYCLOPENTADIENE OR INDENE WITH FLUORENE AND GROUP IV METALS PHILLIPS PETROLEUM COMPANY (US) 1997-05-06 US claimed
WO-2019188644-A1 TRANSITION METAL COMPOUND, CATALYST FOR OLEFIN POLYMERIZATION AND METHOD FOR PRODUCING OLEFIN POLYMER 三井化学株式会社 2019-10-03 WO disclosed
CN-101107260-B Transition metal complex, method for producing the same, substituted fluorene compound, method for producing the substituted fluorene compound, catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer SUMITOMO CHEMICAL CO.,LTD. (JP) 2012-02-08 CN disclosed
CN-101107260-A Transition metal complex, method for producing the same, substituted fluorene compound, method for producing the substituted fluorene compound, catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer SUMITOMO CHEMICAL CO (JP) 2008-01-16 CN disclosed
EP-0849288-B1 Catalyst for polymerization of an olefin, and method for producing an olefin polymer TOSOH CORP (JP) 2002-11-27 EP disclosed
US-5906955-A Catalyst for polymerization of an olefin, and method for producing an olefin polymer TOSOH CORPORATION (JP) 1999-05-25 US disclosed
EP-0849288-A1 Catalyst for polymerization of an olefin, and method for producing an olefin polymer TOSOH CORPORATION (JP) 1998-06-24 EP disclosed