Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.32 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7634193 | 0.85 | EP300 (0.36) | ACHETRPV1KDM4E | |
| SCHEMBL7633997 | 0.74 | HPRT1 (0.32) | HPRT1 | |
| SCHEMBL29728630 | 0.69 | IDO1 (0.46) | IDO1 | |
| SCHEMBL73467 | 0.69 | IDO1 (0.46) | IDO1 | |
| SCHEMBL21065416 | 0.69 | — | — | |
| SCHEMBL15466319 | 0.67 | HPRT1 (0.40) | IDO1HPRT1TRPM4 | |
| Hydrochloric Acid SCHEMBL4151874 | 0.67 | ANPEP (0.48) | IDO1 | |
| Ammonia Solution, Strong SCHEMBL7301670 | 0.67 | IDO1 (0.44) | IDO1 | |
| SCHEMBL24228654 | 0.66 | ACHE (0.30) | ACHE | |
| SCHEMBL21096083 | 0.65 | KDM4E (0.41) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417405-B2 | Synthesis of cyclopentadiene or substituted cyclopentadiene compounds | THE DOW CHEMICAL COMPANY | 2002-07-09 | — | — | US | disclosed |
| US-20020002308-A1 | Synthesis of 4-ketocyclopentene and cyclopentadiene compounds | DOW CHEMICAL COMPANY, THE | 2002-01-03 | — | — | US | disclosed |
| EP-1159245-A1 | SYNTHESIS OF 4-KETOCYCLOPENTENE AND CYCLOPENTADIENE COMPOUNDS | THE DOW CHEMICAL COMPANY (US) | 2001-12-05 | — | — | EP | disclosed |
| US-6310256-B1 | REDUCING 1-CARBOHYDROCARBYLOXY-2-KETO-4-HYDROXY-5-CYCLOPENTENE COMPOUND BY CONTACTING WITH ZINC AND DECARBOXYLATING THE RESULTING REACTION PRODUCT BY CONTACTING THE REACTION MIXTURE WITH A MIXTURE OF AN ORGANIC ACID AND INORGANIC HALIDE | THE DOW CHEMICAL COMPANY | 2001-10-30 | — | — | US | disclosed |
| WO-2000051958-A1 | SYNTHESIS OF 4-KETOCYCLOPENTENE AND CYCLOPENTADIENE COMPOUNDS | THE DOW CHEMICAL COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020002308-A1 | Synthesis of 4-ketocyclopentene and cyclopentadiene compounds | ADH1C, ADH1A, ADH5 | ACHE 3518/4885IDO1 1513/4885HSP90AA1 2335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.