Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAN2A1 | Q16706 | 2/20 | 0.42 |
| ▸ | MAN1B1 | Q9UKM7 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7635018 | 0.84 | ALDH1A1 (0.55) | L3MBTL1MAPTALDH1A1KMT2ALMNA | |
| SCHEMBL28318922 | 0.81 | L3MBTL1 (0.66) | L3MBTL1MAPTALDH1A1KMT2ALMNA | |
| SCHEMBL22716418 | 0.81 | L3MBTL1 (0.57) | L3MBTL1MAPTALDH1A1KMT2ALMNA | |
| SCHEMBL22716417 | 0.81 | L3MBTL1 (0.57) | L3MBTL1MAPTALDH1A1KMT2ALMNA | |
| SCHEMBL5269591 | 0.78 | AOC3 (0.55) | AOC3ALDH1A1KMT2ALMNANPSR1 | |
| SCHEMBL13191170 | 0.78 | AOC3 (0.55) | AOC3ALDH1A1KMT2ALMNANPSR1 | |
| SCHEMBL8795665 | 0.78 | ALDH1A1 (0.49) | L3MBTL1MAPTALDH1A1KMT2AHPGD | |
| SCHEMBL9462452 | 0.77 | MAPT (0.70) | L3MBTL1MAPTALDH1A1KMT2ALMNA | |
| SCHEMBL9462454 | 0.77 | MAPT (0.70) | L3MBTL1MAPTALDH1A1KMT2ALMNA | |
| SCHEMBL10741036 | 0.74 | KDM4E (0.59) | L3MBTL1MAPTAOC3ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171753-A | Derivatives of 2-amino-1-phenylethanol having antiulcer activity | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-12-15 | — | — | US | disclosed |