Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | STS | P08842 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | TACR2 | P21452 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8683079 | 0.80 | CNR2 (0.44) | CNR2 | |
| SCHEMBL6014093 | 0.77 | MEN1 (0.36) | HDAC3HDAC1HDAC2MEN1KMT2A | |
| SCHEMBL8683078 | 0.77 | SHBG (0.41) | SMN1; SMN2SHBGCYP3A4HIF1A | |
| SCHEMBL10512613 | 0.77 | PTGS2 (0.50) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL828819 | 0.77 | PTGS2 (0.50) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL1778094 | 0.77 | PTGS2 (0.50) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL829405 | 0.77 | PTGS2 (0.50) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL4762927 | 0.75 | ESR1 (0.48) | ALDH1A1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL1243639 | 0.75 | PTGS2 (0.40) | ALDH1A1KCNH2ESR1ADRA2AADORA3 | |
| SCHEMBL4624237 | 0.75 | PTGS2 (0.40) | ALDH1A1KCNH2ESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469198-B2 | OBTAINED BY CONTACTING N-SALICYLIDENEAMINOALCOHOL WITH MONO OR DIVALENT COPPER COMPOUND; FORMATION OF OPTICALLY ACTIVE CYCLOPROPANE-CARBOXYLIC ESTER FROM PROCHIRAL OLEFIN AND DIAZOACETIC ACID ESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-10-22 | — | — | US | claimed |
| EP-0128012-B1 | NOVEL CHIRAL COPPER COMPLEX AND ASYMMETRIC SYNTHESIS OF CYCLOPROPANECARBOXYLATE DERIVATIVES USING SAID COMPLEX AS CATALYST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-11-20 | — | — | EP | claimed |