Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | TACR2 | P21452 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10512613 | 1.00 | PTGS2 (0.50) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL1778094 | 1.00 | PTGS2 (0.50) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL829405 | 1.00 | PTGS2 (0.50) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL4762927 | 0.98 | ESR1 (0.48) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL4304642 | 0.98 | ESR1 (0.47) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL1539433 | 0.92 | CA2 (0.42) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL8780465 | 0.91 | ESR1 (0.48) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL10962003 | 0.89 | DNM1 (0.46) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL21268375 | 0.86 | CA2 (0.37) | PTGS2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL192374 | 0.81 | PTGS2 (0.50) | PTGS2ESR1ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569751-B1 | METHODS FOR PREPARING CATALYSTS | EXXONMOBIL RES & ENG CO (US) | 2015-10-07 | — | — | EP | disclosed |
| EP-1718596-B1 | CATALYTIC PREPARATION OF SEVERELY STERICALLY HINDERED AMINO-ETHER ALCOHOLS USING A METAL LOADED CATALYST | EXXONMOBIL RES & ENG CO (US) | 2014-08-27 | — | — | EP | disclosed |
| US-8288025-B2 | High performance polymeric blend membrane materials based on N-heterocycles and acid-base interactions | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-10-16 | — | — | US | disclosed |
| US-8143438-B2 | Hydrogenation processes | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-03-27 | — | — | US | disclosed |
| CN-1717278-B | Process for preparing catalyst | EXXONMOBIL RES & ENG CO | 2011-07-13 | — | — | CN | disclosed |
| US-20110082311-A1 | Hydrogenation Processes | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2011-04-07 | — | — | US | disclosed |
| US-7875742-B2 | hydrogenating organic compounds by contacting with hydrogen-containing gas in presence of catalyst which comprises catalytically active metals applied to porous catalyst support; catalytically active metals having been derived via decomposed amine complex of metal on support | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-01-25 | — | — | US | disclosed |
| US-20100184895-A1 | Hydrogenation Processes | EXXONMOBOIL RESEARCH AND ENGINEERING COMPANY | 2010-07-22 | — | — | US | disclosed |
| US-7732634-B2 | hydrogenating organic compounds by contacting with hydrogen-containing gas in presence of catalyst which comprises catalytically active metals applied to porous catalyst support; catalytically active metals having been derived via decomposed amine complex of metal on support | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-06-08 | — | — | US | disclosed |
| CN-100572355-C | Catalytic preparation of severely sterically hindered amino-ether alcohols using metal-supported catalysts | EXXONMOBIL RES & ENG CO (US) | 2009-12-23 | — | — | CN | disclosed |
| EP-1569751-A2 | METHODS FOR PREPARING CATALYSTS | ExxonMobil Research and Engineering Company (US) | 2005-09-07 | — | — | EP | disclosed |
| CN-1642645-A | Treatment of acid catalysts with nitrogen compounds | EXXONMOBIL CHEM PATENTS INC (US) | 2005-07-20 | — | — | CN | disclosed |
| US-6916965-B2 | Treatment of acid catalysts | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-07-12 | — | — | US | disclosed |
| EP-1490172-A1 | TREATMENT OF ACID CATALYSTS WITH NITROGEN COMPOUNDS | ExxonMobil Chemical Patents Inc. (US) | 2004-12-29 | — | — | EP | disclosed |
| US-20040157732-A1 | Treating an activated metalloaluminophosphate molecular sieve with one or more nitrogen containing compounds (aliphatic, aromatic, hetetrocycic or organonitrile compounds) to chemisorb and/or physisorb nitrogen-compound | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-08-12 | — | — | US | disclosed |
| US-6756516-B2 | Treatment of acid catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-06-29 | — | — | US | disclosed |
| WO-2004046076-A2 | HYDROGENATION CATALYST, PREPARATION THEREOF AND HYDROGENATION PROCESSES USING THIS CATALYST | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2004-06-03 | — | — | WO | disclosed |
| WO-2004045767-A2 | METHODS FOR PREPARING CATALYSTS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2004-06-03 | — | — | WO | disclosed |
| WO-2003084661-A1 | TREATMENT OF ACID CATALYSTS WITH NITROGEN COMPOUNDS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2003-10-16 | — | — | WO | disclosed |
| US-20030004056-A1 | Treatment of acid catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2003-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082311-A1 | Hydrogenation Processes | HAO2, HVCN1, AOC3 | PTGS2 587/4885ESR1 1833/4885ADRA2A 3404/4885 |
| US-20100184895-A1 | Hydrogenation Processes | HAO2, HVCN1, AOC3 | PTGS2 587/4885ESR1 1833/4885ADRA2A 3404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.