Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858546 | 0.89 | TAAR1 (0.34) | MEN1KMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL2578700 | 0.81 | NR1H2 (0.33) | MEN1KMT2ALMNATAAR1NR1H2 | |
| SCHEMBL8683078 | 0.78 | SHBG (0.41) | SMN1; SMN2CYP3A4 | |
| SCHEMBL8683079 | 0.78 | CNR2 (0.44) | — | |
| SCHEMBL7635289 | 0.77 | GHSR (0.40) | MEN1KMT2ASMN1; SMN2LMNAADORA3 | |
| SCHEMBL15063902 | 0.76 | KIF11 (0.41) | TAAR1 | |
| SCHEMBL28310090 | 0.76 | HTR7 (0.35) | KMT2AHTTHDAC3HDAC1HDAC2 | |
| SCHEMBL4625366 | 0.73 | HTT (0.33) | SMN1; SMN2HTT | |
| SCHEMBL21268369 | 0.73 | TAAR1 (0.36) | TAAR1 | |
| SCHEMBL27999537 | 0.73 | TAAR1 (0.41) | KMT2ATAAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615866-A1 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS | Inflazyme Pharmaceuticals, Ltd. (CA) | 2006-01-18 | — | — | EP | claimed |
| WO-2004092100-A1 | INDENE DERIVATIVES AS PHARMACEUTICAL AGENTS | INFLAZYME PHARMACEUTICALS LTD. (CA) | 2004-10-28 | — | — | WO | claimed |