SCHEMBL460957

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1367365	0.92	PARP10 (0.70)	CES2CES1L3MBTL1PARP10NPC1
	SCHEMBL845256	0.89	L3MBTL1 (0.77)	LMNAMAPK1L3MBTL1PARP10NPC1
	SCHEMBL8341465	0.86	PTPRC (0.65)	L3MBTL1PARP10NPC1RAB9AKMT2A
	SCHEMBL11764689	0.85	L3MBTL1 (0.60)	CES2CES1LMNAMAPK1L3MBTL1
	SCHEMBL1979912	0.85	LMNA (0.59)	LMNAMAPK1L3MBTL1PARP10NPC1
	SCHEMBL7635359	0.85	NPC1 (0.64)	CES1LMNAMAPK1L3MBTL1PARP10
	Benzamide SCHEMBL5531824	0.85	PARP10 (0.86)	LMNAMAPK1L3MBTL1PARP10NPC1
	SCHEMBL11234780	0.85	CES2 (0.73)	CES2CES1MAPK1PARP10NPC1
	SCHEMBL13268807	0.85	LTA4H (0.66)	PARP10NPC1RAB9AKMT2AMAPT
	1,4-Diethoxybenzene SCHEMBL28832463	0.85	MAOB (0.64)	LMNAMAPK1L3MBTL1PARP10NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.