Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18360374 | 0.94 | POLB (0.44) | LMNAPLA2G10PLA2G2ALTA4HNR3C1 | |
| SCHEMBL12311123 | 0.85 | ALDH1A1 (0.61) | LTA4HTDP1 | |
| SCHEMBL202173 | 0.83 | TDP1 (0.50) | PLA2G2AAKR1B1CYP2C9TDP1POLB | |
| SCHEMBL8038936 | 0.83 | TDP1 (0.44) | LMNAPLA2G2ANR3C1TDP1KEAP1 | |
| SCHEMBL13644999 | 0.80 | LMNA (0.50) | LMNAFFAR1TDP1 | |
| SCHEMBL13647724 | 0.80 | ALDH1A1 (0.41) | LMNAPLA2G2ALTA4HNR3C1TDP1 | |
| SCHEMBL18719869 | 0.80 | LTA4H (0.35) | LMNAPLA2G10PLA2G2ALTA4HNR3C1 | |
| SCHEMBL5189401 | 0.78 | TSHR (0.57) | LMNANR3C1AKR1B1CNR2POLB | |
| SCHEMBL339416 | 0.78 | ALDH1A1 (0.50) | LMNAPLA2G2APOLB | |
| SCHEMBL7637806 | 0.77 | TSHR (0.46) | LMNANR3C1FFAR1TDP1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458869-B1 | ETCHANT/PRIMER COMPOSITION, AN ETCHANT/PRIMER/ADHESIVE MONOMER COMPOSITION, KITS USING THE SAME AND METHODS USING THE SAME FOR IMPROVED BONDING TO DENTAL STRUCTURES. THE ETCHANT/PRIMER COMPOSITION COMPRISES A COMPOUND HAVING THE | NATIONAL INSTITUTE OF STANDARDS OF TECHNOLOGY | 2002-10-01 | — | — | US | disclosed |