SCHEMBL7635691

SCHEMBL7635691

Cc1ccc(S(=O)(=O)OC(C)c2ccc(F)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.42
BCHE P06276 1/20 0.42
AKR1C3 P42330 1/20 0.41
AGER Q15109 1/20 0.40
KMT2A Q03164 5/20 0.40
MEN1 O00255 3/20 0.40
VDR P11473 1/20 0.40
GAA P10253 2/20 0.39
PAX8 Q06710 1/20 0.39
TP53 P04637 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 3/20 0.39
LMNA P02545 2/20 0.39
HTT P42858 2/20 0.39
EGFR P00533 1/20 0.38
ERBB2 P04626 1/20 0.38
TSHR P16473 1/20 0.38
USP2 O75604 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7637176 0.92 GAA (0.45) ACHEBCHEAGERKMT2AMEN1
SCHEMBL28626138 0.84 ALDH1A1 (0.42) ACHEBCHEAGERKMT2AMEN1
SCHEMBL11988007 0.83 VDR (0.45) VDRGAAALDH1A1HTTMAPT
SCHEMBL491994 0.83 VDR (0.45) VDRGAAALDH1A1HTTMAPT
SCHEMBL18037162 0.81 VDR (0.41) VDRALDH1A1LMNAHTTMAPT
SCHEMBL28934795 0.81 KMT2A (0.43) AGERKMT2AMEN1VDRGAA
SCHEMBL16344772 0.81 KMT2A (0.43) AGERKMT2AMEN1VDRGAA
SCHEMBL4731994 0.80 ACHE (0.39) ACHEBCHEAKR1C3KMT2AMEN1
SCHEMBL29028756 0.80 EPAS1 (0.40) AGERKMT2AALDH1A1
SCHEMBL9508775 0.79 AGER (0.41) AGERKMT2AMEN1VDRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1203771-A1 REMEDIES OR PREVENTIVES FOR FREQUENT URINATION OR URINARY INCONTINENCE TORAY INDUSTRIES, INC. (JP) 2002-05-08 EP disclosed