Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3453810 | 0.75 | ALDH1A1 (0.40) | ALDH1A1ALOX15HSD17B10CYP3A4LMNA | |
| SCHEMBL3682829 | 0.75 | ALDH1A1 (0.40) | ALDH1A1ALOX15HSD17B10CYP3A4LMNA | |
| SCHEMBL1682370 | 0.74 | CYP3A4 (0.45) | ALDH1A1ALOX15HSD17B10CYP3A4LMNA | |
| SCHEMBL11716898 | 0.74 | ALDH1A1 (0.39) | ALDH1A1ALOX15HSD17B10CYP3A4LMNA | |
| SCHEMBL3687350 | 0.72 | TDP1 (0.38) | ALDH1A1ALOX15HSD17B10CYP3A4LMNA | |
| SCHEMBL9857101 | 0.70 | ALDH1A1 (0.43) | ALDH1A1ALOX15HSD17B10CYP3A4LMNA | |
| SCHEMBL1485970 | 0.70 | ALDH1A1 (0.43) | ALDH1A1ALOX15HSD17B10CYP3A4LMNA | |
| SCHEMBL1585638 | 0.69 | ALDH1A1 (0.42) | ALDH1A1ALOX15HSD17B10CYP3A4LMNA | |
| SCHEMBL4966366 | 0.68 | MGAM (0.44) | ALDH1A1ALOX15HSD17B10CYP3A4LMNA | |
| SCHEMBL19204143 | 0.68 | ALDH1A1 (0.33) | ALDH1A1LMNATSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395920-B1 | OBTAINING 2-SUBSTITUTED AND 2,2- DISUBSTITUTED ACETALS OF MALONDIALDEHYDE FROM ORTHO FORMATES AND SUBSTITUTED VINYL ETHERS IN THE PRESENCE OF AN ACIDIC CATALYST | CREANOVA, INC. | 2002-05-28 | — | — | US | disclosed |
| US-20020040166-A1 | PROCESS FOR PREPARING SUBSTITUTED ACETALS OF MALONDIALDEHYDE | CREANOVA, INC. | 2002-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020040166-A1 | PROCESS FOR PREPARING SUBSTITUTED ACETALS OF MALONDIALDEHYDE | AOX1, GPX4, NOX4 | ALDH1A1 32/4885ALOX15 287/4885HSD17B10 323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.