SCHEMBL7638231

SCHEMBL7638231

CCCCOB(OCCCC)Oc1c(C(C)(C)C)cccc1C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.35
CA2 P00918 1/20 0.33
GAA P10253 1/20 0.32
KDM4E B2RXH2 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LTA4H P09960 2/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
TSHR P16473 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
NLRP3 Q96P20 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL717885 0.83 CYP3A4 (0.39) ALDH1A1CA2SMN1; SMN2CYP2C9CYP2C19
SCHEMBL9364029 0.79 CYP3A4 (0.39) ALDH1A1CA2SMN1; SMN2CYP2C9CYP2C19
SCHEMBL27934690 0.79 ALDH1A1 (0.46) ALDH1A1CA2GAAKDM4ESMN1; SMN2
SCHEMBL10406812 0.78 CA2 (0.46) ALDH1A1CA2KDM4ESMN1; SMN2TSHR
SCHEMBL29015759 0.73 GAA (0.34) GAAL3MBTL1
SCHEMBL12646952 0.72 ALDH1A1 (0.46) ALDH1A1CA2GAAKDM4ESMN1; SMN2
SCHEMBL12646949 0.72 NPC1 (0.40) ALDH1A1CA2GAAKDM4ESMN1; SMN2
SCHEMBL8022872 0.70 LTA4H (0.53) ALDH1A1SMN1; SMN2LTA4HCYP1A2CYP2C9
SCHEMBL22174387 0.70 NLRP3 (0.31) ALDH1A1CA2KDM4ESMN1; SMN2NLRP3
SCHEMBL28425057 0.70 TSHR (0.44) ALDH1A1CA2GAAKDM4ELTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1186588-A1 6-HYDROXY-2-NAPHTHYLCARBINOL AND PROCESS FOR THE PREPARATION THEREOF MITSUBISHI CHEMICAL CORPORATION (JP) 2002-03-13 EP disclosed
US-4927553-A LUBRICANT CONTAINING BORONATED PHENOLIC ANTIOXIDANT AND ANTI-HAZE DIOL ETHYL CORPORATION (US) 1990-05-22 US disclosed
US-4623360-A ANTICOKING, ORGANIC NITRATES AND BORATED PHENOLIC COMPOUND ETHYL CORPORATION (US) 1986-11-18 US disclosed
US-4530770-A Oxidation resistance MOBIL OIL CORPORATION (US) 1985-07-23 US disclosed
US-4192770-A METAL CONTAMINANTS SHELL OIL COMPANY (US) 1980-03-11 US disclosed