Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7638296 | 0.91 | APEX1 (0.36) | APEX1TRPV1 | |
| SCHEMBL10536720 | 0.81 | CA12 (0.35) | MAPTTDP1L3MBTL1EGFRSMN1; SMN2 | |
| SCHEMBL8026135 | 0.80 | APEX1 (0.37) | APEX1MAPTTDP1L3MBTL1MEN1 | |
| SCHEMBL379576 | 0.80 | RXRA (0.33) | NPSR1RXRARXRBRXRGHTT | |
| SCHEMBL10576616 | 0.78 | LMNA (0.34) | MAPTTDP1L3MBTL1EGFRSMN1; SMN2 | |
| SCHEMBL997016 | 0.77 | KDM4E (0.33) | APEX1L3MBTL1SMN1; SMN2TRPV1CYP2C19 | |
| SCHEMBL1074119 | 0.76 | RXRA (0.31) | RXRARXRBRXRGCYP2C19RARG | |
| SCHEMBL11655989 | 0.76 | APEX1 (0.46) | APEX1MAPTTDP1L3MBTL1 | |
| SCHEMBL29350333 | 0.75 | APEX1 (0.50) | APEX1MAPTTDP1L3MBTL1SMN1; SMN2 | |
| SCHEMBL76989 | 0.75 | APEX1 (0.50) | APEX1MAPTTDP1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416321-B1 | Crystalline polyolefin composition | CHISSO CORP (JP) | 1994-11-09 | — | — | EP | disclosed |
| US-5063264-A | Molding materials | CHISSO CORPORATION (JP) | 1991-11-05 | — | — | US | disclosed |
| EP-0416321-A1 | Crystalline polyolefin composition | Chisso Corporation (JP) | 1991-03-13 | — | — | EP | disclosed |