SCHEMBL7638853

SCHEMBL7638853

CCCCc1ccc(C(=O)CC(=O)c2ccccc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.65
HAO1 Q9UJM8 1/20 0.65
RARB P10826 2/20 0.60
PLK1 P53350 1/20 0.60
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
HPGD P15428 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
KDM4E B2RXH2 1/20 0.59
CYP3A4 P08684 1/20 0.59
MAPT P10636 1/20 0.59
ALOX15 P16050 1/20 0.59
CES1 P23141 1/20 0.59
MAPK1 P28482 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
NPC1 O15118 2/20 0.58
RAB9A P51151 2/20 0.58
THRA P10827 4/20 0.57
THRB P10828 4/20 0.57
CASP3 P42574 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11053940 0.93 HAO1 (0.75) HAO1RARBPLK1MEN1KMT2A
SCHEMBL10790094 0.93 HAO1 (0.75) HAO1RARBPLK1MEN1KMT2A
SCHEMBL7633932 0.93 PLK1 (0.68) TRPV1HAO1RARBPLK1HPGD
SCHEMBL7634965 0.89 L3MBTL1 (0.64) TRPV1HAO1PLK1MEN1KMT2A
SCHEMBL8561239 0.86 ALDH1A1 (0.66) TRPV1HAO1RARBPLK1HPGD
SCHEMBL12620502 0.86 HAO1 (0.60) TRPV1HAO1RARBPLK1MEN1
SCHEMBL1577439 0.86 HAO1 (0.79) HAO1RARBMEN1KMT2AMAPT
SCHEMBL4603474 0.86 TRPV1 (0.64) TRPV1RARBPLK1MEN1KMT2A
SCHEMBL13746080 0.85 ALDH1A1 (0.64) TRPV1HAO1RARBPLK1HPGD
SCHEMBL28013341 0.85 THRA (0.64) TRPV1HAO1RARBPLK1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110325168-A Personal care compositions containing cystine 荷兰联合利华有限公司 2019-10-11 CN disclosed
CN-110121332-A Personal care compositions with glutathione precursors comprising nicotinamide and amino acids 荷兰联合利华有限公司 2019-08-13 CN disclosed
CN-110121329-A Local skin blast additive and composition with amino acid and PPAR activation fatty acid 荷兰联合利华有限公司 2019-08-13 CN disclosed
CN-110121330-A Personal care compositions with glutathione precursors comprising 4-substituted resorcinols and amino acids 荷兰联合利华有限公司 2019-08-13 CN disclosed
CN-110099672-A Topical skin lightening additives and compositions with amino acid and nicotinamide compounds 荷兰联合利华有限公司 2019-08-06 CN disclosed
CN-105050569-B Cosmetic compositions and methods providing enhanced skin care active penetration 宝洁公司 2019-04-19 CN disclosed
CN-109562043-A Personal care composition comprising fatty acid amide derivant 荷兰联合利华有限公司 2019-04-02 CN disclosed
CN-109312077-A Curable silicon composition and its application and use 莫门蒂夫性能材料股份有限公司 2019-02-05 CN disclosed
CN-108289811-A Sun care preparations 株式会社资生堂 2018-07-17 CN disclosed
CN-105377221-A Composition containing thermal regulating material ELC MAN LLC 2016-03-02 CN disclosed
CN-104968320-A Cosmetic compositions having Near Infrared (NIR) light emitting materials and methods thereof ELC MAN LLC 2015-10-07 CN disclosed
CN-104968319-A Cosmetic compositions with near infra-red (NIR) light-emitting material and methods therefor ELC MAN LLC 2015-10-07 CN disclosed
CN-104968321-A Cosmetic compositions having Near Infrared (NIR) light emitting materials and methods thereof ELC MAN LLC 2015-10-07 CN disclosed
CN-104955437-A Cosmetic compositions with near infra-red (NIR) light-emitting material and methdos therefor ELC MAN LLC 2015-09-30 CN disclosed
CN-104902872-A Methods and compositions for improving selective catabolism and viability in cells on the surface of keratin ELC MAN LLC 2015-09-09 CN disclosed
CN-104797237-A Methods and compositions for improving selective catabolism in cells on the surface of keratin ELC MAN LLC 2015-07-22 CN disclosed
CN-104780897-A COSMETIC COMPOSITIONS AND METHODS FOR INHIBITING MELANIN SYNTHESIS PROCTER & GAMBLE 2015-07-15 CN disclosed
CN-104768525-A Cosmetic compositions and methods for inhibiting melanin synthesis PROCTER & GAMBLE 2015-07-08 CN disclosed
CN-104755068-A sunscreen composition UNILEVER NV 2015-07-01 CN disclosed
US-6448304-B1 POLYURETHANE, POLYTHIOURETHANE OR DIETHYLENE GLYCOL BISALLYLCARBONATE POLYMER; DIPPING IN SOLUTION CONTAINING A DIBENZOYLMETHANE OR A BENZOTRIZOLE COMPOUND; PLASTIC LENS FOR SPECTACLES WHICH ABSORBS ULTRAVIOLET RAYS; LOW YELLOWNESS HOYA CORPORATION (JP) 2002-09-10 US disclosed