Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532393 | 0.83 | RAB9A (0.47) | SMN1; SMN2ATMALDH1A1MEN1KMT2A | |
| SCHEMBL7463048 | 0.72 | CYP3A4 (0.57) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL7470064 | 0.72 | CPB1 (0.48) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7478638 | 0.71 | MEN1 (0.50) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7470299 | 0.71 | MGLL (0.62) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL7470042 | 0.71 | MGLL (0.61) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL27511900 | 0.70 | MEN1 (0.56) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7637970 | 0.68 | MEN1 (0.50) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7463271 | 0.68 | RAB9A (0.60) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL17065056 | 0.68 | ALDH1A1 (0.64) | SMN1; SMN2ATMALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458959-B1 | VIRICIDES AND ENZYME INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-10-01 | — | — | US | disclosed |
| US-6348477-B1 | SUBSTITUTED PHENYL THIAZOLE DERIVATIVES AS VIRICIDES | BOEHRINGER INGELHEIM(CANADA) LTD. (CA) | 2002-02-19 | — | — | US | disclosed |
| US-6288091-B1 | COMPOUNDS SUCH AS 2,2,2-TRICHLOROETHYL N-(4-(2-AMINO-4-THIAZOLYL)-PHENYL)CARBAMATE THAT INHIBIT THE HERPES HELCASE-PRIMASE ENZYME COMPLEX | BOEHRINGER INGELHEIM LTD. (CA) | 2001-09-11 | — | — | US | disclosed |
| US-6057451-A | AMINOTHIAZOLE DERIVATIVES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-05-02 | — | — | US | disclosed |