Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 7/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7643697 | 0.90 | PTGDR (0.38) | PTGDRFAAHTBXA2RTHRBCNR2 | |
| SCHEMBL6865579 | 0.78 | PTGDR (0.35) | PTGDRFAAHTBXA2RCNR2MEN1 | |
| SCHEMBL7643696 | 0.76 | PTGDR (0.55) | PTGDRTBXA2R | |
| SCHEMBL6869923 | 0.69 | PTGDR (0.39) | PTGDRFAAHTBXA2RMEN1USP2 | |
| SCHEMBL14514987 | 0.64 | PTGDR (0.67) | PTGDRTBXA2RHDAC1HDAC6HDAC3 | |
| SCHEMBL4648170 | 0.64 | PTGDR (0.74) | PTGDRTBXA2R | |
| SCHEMBL6866936 | 0.64 | PTGDR (0.74) | PTGDRTBXA2R | |
| SCHEMBL6866940 | 0.64 | PTGDR (0.74) | PTGDRTBXA2R | |
| SCHEMBL1761699 | 0.61 | HDAC1 (0.51) | PTGDRFAAHTBXA2RCNR2MEN1 | |
| SCHEMBL12586230 | 0.60 | HSD11B1 (0.53) | HDAC1HDAC6HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020161242-A1 | Process for preparing benzothiophenecarboxamide derivatives | HONMA TSUNETOSHI (JP) | 2002-10-31 | — | — | US | disclosed |
| US-20020156297-A1 | Process for preparing benzothiophenecarboxamide derivatives | OKADA TETSUO (JP) | 2002-10-24 | — | — | US | disclosed |
| US-6462241-B2 | REACTING AN AMINO ALCOHOL WITH A BENZOTHIOPHENE, REACTING THE PRODUCT WITH A HALO OXACID IN THE PRESENCE OF 2,2,6,6-TETRA METHYLPIPERIDINE-1-OXYLS, FURTHER REACTING WITH AN YLIDE UNDER WITTIG REACTION CONDITIONS AND DEPROTECTING | SHIONOGI & CO., LTD. (JP) | 2002-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020161242-A1 | Process for preparing benzothiophenecarboxamide derivatives | PGD, HPD, PTGS2 | PTGDR 11/4885FAAH 602/4885TBXA2R 34/4885 |
| US-20020156297-A1 | Process for preparing benzothiophenecarboxamide derivatives | PGD, HPD, PTGS2 | PTGDR 11/4885FAAH 602/4885TBXA2R 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.