Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL11150398 | 1.00 | LMNA (0.47) | LMNACASP1ADORA2AADORA1POLB | |
| Ethylene SCHEMBL2038444 | 1.00 | LMNA (0.47) | LMNACASP1ADORA2AADORA1POLB | |
| Ethylene SCHEMBL3132468 | 0.95 | LMNA (0.45) | LMNACASP1ADORA2AADORA1POLB | |
| SCHEMBL29485005 | 0.89 | — | — | |
| SCHEMBL9583239 | 0.89 | CASP1 (0.50) | LMNACASP1ADORA2AADORA1POLB | |
| SCHEMBL25853 | 0.89 | — | — | |
| SCHEMBL8465809 | 0.89 | CASP1 (0.50) | LMNACASP1ADORA2AADORA1POLB | |
| SCHEMBL9579151 | 0.89 | CASP1 (0.50) | LMNACASP1ADORA2AADORA1POLB | |
| SCHEMBL29876207 | 0.89 | — | — | |
| SCHEMBL29900242 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1492 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250275946-A1 | COMBINATION THERAPY FOR THE TREATMENT OF CANCER | UNM RAINFOREST INNOVATIONS (US) | 2025-09-04 | — | — | US | claimed |
| US-12325755-B2 | Macropinocytosing human anti-CD46 antibodies and targeted cancer therapeutics | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-06-10 | — | — | US | claimed |
| US-20240203601-A1 | ANALYZING COPY NUMBER VARIATION IN THE DETECTION OF CANCER | VERINATA HEALTH, INC. | 2024-06-20 | — | — | US | claimed |
| EP-3383920-B1 | TUMOR-SPECIFIC PAYLOAD DELIVERY AND IMMUNE ACTIVATION USING A HUMAN ANTIBODY TARGETING A HIGHLY SPECIFIC TUMOR CELL SURFACE ANTIGEN | UNIV CALIFORNIA (US) | 2024-01-10 | — | — | EP | claimed |
| US-20230383005-A1 | ANTI-CD46 ANTIBODIES AND METHODS OF USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-11-30 | — | — | US | claimed |
| WO-2022169634-A9 | COMBINATION THERAPY FOR THE TREATMENT OF CANCER | UNM RAINFOREST INNOVATIONS (US) | 2022-09-22 | — | — | WO | claimed |
| US-11447563-B2 | Tumor selective macropinocytosis-dependent rapidly internalizing antibodies | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-09-20 | — | — | US | claimed |
| US-11434301-B2 | Anti-CD46 antibodies and methods of use | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-09-06 | — | — | US | claimed |
| WO-2022169634-A1 | COMBINATION THERAPY FOR THE TREATMENT OF CANCER | UNM RAINFOREST INNOVATIONS (US) | 2022-08-11 | — | — | WO | claimed |
| US-11219697-B2 | Osteoadsorptive fluorogenic substrate of cathepsin k for imaging osteoclast activity and migration | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-01-11 | — | — | US | claimed |
| WO-2006027231-A1 | METHODS FOR THE PRODUCTION OF IMPROVED LIVE STOCKS AND DISEASE MODELS FOR THERAPEUTIC RESEARCH | INGENIUM PHARMACEUTICALS AG (DE) | 2006-03-16 | — | — | WO | claimed |
| WO-2006018316-A1 | METHODS FOR THE PRODUCTION OF IMPROVED LIVE STOCKS AND DISEASE MODELS FOR THERAPEUTIC RESEARCH | INGENIUM PHARMACEUTICALS AG (DE) | 2006-02-23 | — | — | WO | claimed |
| WO-2006002902-A2 | METHODS FOR THE PRODUCTION OF IMPROVED LIVE STOCKS AND DISEASE MODELS FOR THERAPEUTIC RESEARCH | INGENIUM PHARMACEUTICALS AG (DE) | 2006-01-12 | — | — | WO | claimed |
| WO-2005107447-A2 | METHODS FOR THE PRODUCTION OF IMPROVED LIVE STOCKS AND DISEASE MODELS FOR THERAPEUTIC RESEARCH | INGENIUM PHARMACEUTICALS AG (DE) | 2005-11-17 | — | — | WO | claimed |
| EP-1088055-A4 | ALLELIC SERIES OF GENOMIC MODIFICATIONS IN CELLS | UNIV CASE WESTERN RESERVE (US) | 2005-10-19 | — | — | EP | claimed |
| US-20040180955-A1 | Methods and compositions to determine the chemosensitizing dose of suramin used in combination therapy | AU JESSIE L-S (US) | 2004-09-16 | — | — | US | claimed |
| EP-1429713-A2 | METHODS AND COMPOSITIONS TO DETERMINE THE CHEMOSENSITIZING DOSE OF SURAMIN USED IN COMBINATION THERAPY | Au, Jessie L.S. (US) | 2004-06-23 | — | — | EP | claimed |
| WO-2003026574-A2 | METHODS AND COMPOSITIONS TO DETERMINE THE CHEMOSENSITIZING DOSE OF SURAMIN USED IN COMBINATION THERAPY | AU JESSIE L-S (US) | 2003-04-03 | — | — | WO | claimed |
| EP-1088055-A1 | ALLELIC SERIES OF GENOMIC MODIFICATIONS IN CELLS | Case Western Reserve University (US) | 2001-04-04 | — | — | EP | claimed |
| WO-1999067361-A1 | ALLELIC SERIES OF GENOMIC MODIFICATIONS IN CELLS | CASE WESTERN RESERVE UNIVERSITY (US) | 1999-12-29 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11219697-B2 | Osteoadsorptive fluorogenic substrate of cathepsin k for imaging osteoclast activity and migration | CTSS, CTSK, CTSF | LMNA 2373/4885CASP1 84/4885ADORA2A 4048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.