Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12063910 | 0.79 | LMNA (0.38) | LMNACYP2D6 | |
| SCHEMBL25586262 | 0.78 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL1100489 | 0.73 | LMNA (0.35) | LMNACYP2D6 | |
| SCHEMBL16579863 | 0.73 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL20434567 | 0.73 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL38006 | 0.71 | — | — | |
| SCHEMBL14943806 | 0.71 | LMNA (0.33) | LMNACYP2D6 | |
| SCHEMBL25920321 | 0.71 | LMNA (0.33) | LMNACYP2D6 | |
| SCHEMBL10296019 | 0.71 | LMNA (0.33) | LMNACYP2D6 | |
| SCHEMBL172037 | 0.69 | EPHX1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1439174-B1 | 4-IMIDAZOLIN-2-ONE COMPOUNDS AS p38 MAP KINASE INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-03-21 | — | — | EP | disclosed |