Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7642639 | 0.67 | CA12 (0.34) | ALDH1A1CA12CA7CA9CA14 | |
| SCHEMBL6238673 | 0.65 | MTNR1A (0.45) | ALDH1A1LMNAGRIA4TP53MEN1 | |
| SCHEMBL2022136 | 0.64 | LMNA (0.33) | ALDH1A1LMNACA12CA7CA9 | |
| SCHEMBL18051140 | 0.63 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL5317775 | 0.62 | LMNA (0.34) | ALDH1A1LMNAHTTTP53MAPT | |
| SCHEMBL9861266 | 0.62 | NPSR1 (0.38) | LMNAHTTTP53MEN1KMT2A | |
| SCHEMBL13754063 | 0.61 | ALDH1A1 (0.40) | ALDH1A1LMNAHTT | |
| SCHEMBL10824109 | 0.61 | LMNA (0.37) | ALDH1A1LMNAHTTKMT2AMMP8 | |
| SCHEMBL4617578 | 0.61 | LMNA (0.37) | ALDH1A1LMNAHTTMAPT | |
| SCHEMBL15269466 | 0.60 | TRPA1 (0.33) | LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |