Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28297388 | 0.82 | ALDH1A1 (0.42) | KCNA3MAPTALDH1A1TSHRPKM | |
| SCHEMBL7638951 | 0.81 | ALDH1A1 (0.51) | KCNA3MAPTEPAS1ALDH1A1TSHR | |
| SCHEMBL7634824 | 0.81 | EPAS1 (0.56) | MAOBKCNA3MAPTEPAS1ALDH1A1 | |
| SCHEMBL7638472 | 0.81 | GAA (0.48) | MAOBKCNA3MAPTEPAS1ALDH1A1 | |
| SCHEMBL7640758 | 0.81 | MAOB (0.43) | MAOBKCNA3EPAS1ALDH1A1TSHR | |
| SCHEMBL3259136 | 0.74 | NOTUM (0.45) | MAPTCA12CA9KDM4E | |
| SCHEMBL30566709 | 0.74 | MAOB (0.36) | MAOBKCNA3CA12CA2CA9 | |
| SCHEMBL31154056 | 0.73 | ALDH1A1 (0.46) | KCNA3MAPTALDH1A1TSHRCA12 | |
| SCHEMBL28068111 | 0.72 | GAA (0.56) | KCNA3ALDH1A1TSHRPKMGAA | |
| SCHEMBL28619635 | 0.72 | EPAS1 (0.71) | MAPTEPAS1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458962-B1 | VIRICIDES FOR TREATMENT OF AIDS AND HYDROGENATION OF COMPOUNDS | THE UNIVERSITY OF TENNESSEEE RESEARCH CORPORATION | 2002-10-01 | — | — | US | disclosed |