Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7638951 | 0.81 | ALDH1A1 (0.51) | RAB9AEPAS1ALDH1A1KCNA3TSHR | |
| SCHEMBL7638472 | 0.81 | GAA (0.48) | MAOBNPC1RAB9AEPAS1ALDH1A1 | |
| SCHEMBL7642811 | 0.81 | MAOB (0.43) | MAOBEPAS1ALDH1A1KCNA3TSHR | |
| SCHEMBL7634824 | 0.81 | EPAS1 (0.56) | MAOBNPC1RAB9AEPAS1ALDH1A1 | |
| SCHEMBL28357548 | 0.78 | PTGES (0.63) | ALDH1A1PTGESPTGS2SMN1; SMN2 | |
| SCHEMBL30566750 | 0.74 | HSP90AA1 (0.44) | MAOBIMPDH2IMPDH1RAB9AALDH1A1 | |
| SCHEMBL31154056 | 0.73 | ALDH1A1 (0.46) | IMPDH2IMPDH1ALDH1A1KCNA3MEN1 | |
| SCHEMBL28297388 | 0.72 | ALDH1A1 (0.42) | RAB9AALDH1A1KCNA3TSHRPKM | |
| SCHEMBL28068111 | 0.72 | GAA (0.56) | ALDH1A1KCNA3MEN1KMT2ATSHR | |
| SCHEMBL2204559 | 0.71 | MEN1 (0.44) | NPC1RAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116621829-A | Synthesis method and application of chiral tetrahydropyran compound | 常州大学 | 2023-08-22 | — | — | CN | disclosed |
| US-6458962-B1 | VIRICIDES FOR TREATMENT OF AIDS AND HYDROGENATION OF COMPOUNDS | THE UNIVERSITY OF TENNESSEEE RESEARCH CORPORATION | 2002-10-01 | — | — | US | disclosed |