Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7638951 | 0.81 | ALDH1A1 (0.51) | EPAS1ALDH1A1KCNA3TSHRPKM | |
| SCHEMBL7638472 | 0.81 | GAA (0.48) | EPAS1MAOBALDH1A1KCNA3PKM | |
| SCHEMBL7642811 | 0.81 | MAOB (0.43) | EPAS1MAOBALDH1A1KCNA3TSHR | |
| SCHEMBL7640758 | 0.81 | MAOB (0.43) | EPAS1MAOBALDH1A1KCNA3TSHR | |
| SCHEMBL31154056 | 0.73 | ALDH1A1 (0.46) | ALDH1A1KCNA3TSHRCA12CA9 | |
| SCHEMBL28068111 | 0.72 | GAA (0.56) | ALDH1A1KCNA3TSHRPKMSMN1; SMN2 | |
| SCHEMBL28297388 | 0.72 | ALDH1A1 (0.42) | ALDH1A1KCNA3TSHRPKMRAB9A | |
| SCHEMBL30896648 | 0.72 | ALDH1A1 (0.70) | EPAS1ALDH1A1KCNA3CA12CA2 | |
| SCHEMBL2204923 | 0.71 | S100A4 (0.45) | EPAS1 | |
| SCHEMBL11459904 | 0.70 | ALDH1A1 (0.59) | EPAS1ALDH1A1KCNA3TSHRCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458962-B1 | VIRICIDES FOR TREATMENT OF AIDS AND HYDROGENATION OF COMPOUNDS | THE UNIVERSITY OF TENNESSEEE RESEARCH CORPORATION | 2002-10-01 | — | — | US | disclosed |