Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28297388 | 0.85 | ALDH1A1 (0.42) | ALDH1A1KCNA3TSHRPKMKDM4E | |
| SCHEMBL28068111 | 0.85 | GAA (0.56) | ALDH1A1KCNA3TSHRPKMLMNA | |
| SCHEMBL31154056 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KCNA3TSHRPKMKDM4E | |
| SCHEMBL7642811 | 0.81 | MAOB (0.43) | ALDH1A1KCNA3TSHRPKMKDM4E | |
| SCHEMBL7634824 | 0.81 | EPAS1 (0.56) | ALDH1A1KCNA3TSHRPKMKDM4E | |
| SCHEMBL7638472 | 0.81 | GAA (0.48) | ALDH1A1KCNA3PKMMAPTRAB9A | |
| SCHEMBL7640758 | 0.81 | MAOB (0.43) | ALDH1A1KCNA3TSHRPKMRAB9A | |
| SCHEMBL7633990 | 0.77 | LMNA (0.55) | ALDH1A1KCNA3PKMLMNAGAA | |
| SCHEMBL11119530 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KCNA3TSHRPKMKDM4E | |
| SCHEMBL11459904 | 0.76 | ALDH1A1 (0.59) | ALDH1A1KCNA3TSHRPKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433149-B1 | Serotonin antagonists, their preparation and pharmaceuticals containing them | RHONE POULENC SANTE (FR) | 1994-02-16 | — | — | EP | claimed |
| CN-106866574-B | A kind of method of reduction amination synthesis of chiral sulfanilamide (SN) in palladium chtalyst asymmetric molecult | 中国科学院大连化学物理研究所 | 2019-06-04 | — | — | CN | disclosed |
| CN-105693653-A | Method for synthesizing chiral amine through palladium catalyzed asymmetric hydrogenolysis of racemic oxazirine | 中国科学院大连化学物理研究所 | 2016-06-22 | — | — | CN | disclosed |
| US-6458962-B1 | VIRICIDES FOR TREATMENT OF AIDS AND HYDROGENATION OF COMPOUNDS | THE UNIVERSITY OF TENNESSEEE RESEARCH CORPORATION | 2002-10-01 | — | — | US | disclosed |
| US-5130313-A | Central nervous system disorders, cardiovascular disorders or gastrointestinal disorders | RHONE-POULENC SANTE (FR) | 1992-07-14 | — | — | US | disclosed |
| US-5114949-A | Treating disorders associated with 5HT uptake | RHONE-POULENC SANTE (FR) | 1992-05-19 | — | — | US | disclosed |
| US-4255578-A | Synthesis of perhalomethylcarbinol-substituted phenol and naphthol sulfamphthalein dyes from the corresponding triacylated derivatives | POLAROID CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
| US-4210752-A | Synthesis of substituted sulfam(na)phthaleins | POLAROID CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |