Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7638951 | 0.85 | ALDH1A1 (0.51) | GAAHTTHSD17B10LMNAPKM | |
| SCHEMBL28297388 | 0.83 | ALDH1A1 (0.42) | GAAHTTHSD17B10POLBLMNA | |
| SCHEMBL7638472 | 0.82 | GAA (0.48) | GAAHTTMEN1KMT2AHSD17B10 | |
| SCHEMBL7633990 | 0.79 | LMNA (0.55) | GAAHTTMEN1KMT2AHSD17B10 | |
| SCHEMBL652970 | 0.74 | PKM (0.53) | GAAHTTMEN1KMT2AHSD17B10 | |
| SCHEMBL31154056 | 0.73 | ALDH1A1 (0.46) | HTTMEN1KMT2AHSD17B10LMNA | |
| SCHEMBL7640758 | 0.72 | MAOB (0.43) | MEN1KMT2APKMALDH1A1SMN1; SMN2 | |
| SCHEMBL7642811 | 0.72 | MAOB (0.43) | GAAHSD17B10POLBPKMALDH1A1 | |
| SCHEMBL7634824 | 0.72 | EPAS1 (0.56) | GAAMEN1KMT2APOLBPKM | |
| SCHEMBL2207008 | 0.71 | GAA (0.44) | GAAHTTMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106866574-B | A kind of method of reduction amination synthesis of chiral sulfanilamide (SN) in palladium chtalyst asymmetric molecult | 中国科学院大连化学物理研究所 | 2019-06-04 | — | — | CN | disclosed |
| CN-105693653-A | Method for synthesizing chiral amine through palladium catalyzed asymmetric hydrogenolysis of racemic oxazirine | 中国科学院大连化学物理研究所 | 2016-06-22 | — | — | CN | disclosed |