Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 11/20 | 0.39 |
| ▸ | CA1 | P00915 | 10/20 | 0.39 |
| ▸ | CA2 | P00918 | 10/20 | 0.39 |
| ▸ | CA9 | Q16790 | 10/20 | 0.39 |
| ▸ | CA7 | P43166 | 5/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7642248 | 0.74 | PTGS2 (0.36) | CA12CA1CA2CA7SMN1; SMN2 | |
| SCHEMBL6909701 | 0.67 | ALDH1A1 (0.44) | CA12CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL6913710 | 0.66 | L3MBTL1 (0.37) | CA12CA1CA2CA9CA7 | |
| SCHEMBL6908277 | 0.66 | PTGS1 (0.41) | CA12CA1CA2CA9CA7 | |
| SCHEMBL1128972 | 0.63 | CA2 (0.51) | CA12CA1CA2CA9CA7 | |
| SCHEMBL7977965 | 0.61 | PTGS1 (0.42) | CA12CA1CA2CA9CA7 | |
| SCHEMBL27821451 | 0.59 | CYP1A2 (0.64) | PTGES2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL30296408 | 0.59 | CA2 (0.46) | CA12CA1CA2CA9CA7 | |
| SCHEMBL25179640 | 0.59 | KCNH2 (0.48) | SMN1; SMN2MAOBALDH1A1 | |
| SCHEMBL27029743 | 0.57 | CA1 (0.52) | CA12CA1CA2CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432994-B1 | CARDIOVASCULAR DISORDERS, GLAUCOMA; ANTIINFLAMMATORY, WOUND HEALING, HYPOTENSIVE, ANTIASTHMATIC, AND ANTIANAPHYLACTIC AGENTS | TEXAS BIOTECHNOLOGY CORPORATION | 2002-08-13 | — | — | US | disclosed |