Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | RXRA | P19793 | 8/20 | 0.59 |
| ▸ | RXRB | P28702 | 7/20 | 0.58 |
| ▸ | RXRG | P48443 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14715123 | 0.94 | NPC1 (0.57) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29118546 | 0.91 | NPC1 (0.54) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| Benzoic Acid SCHEMBL29002939 | 0.88 | NR4A2 (0.59) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10709493 | 0.84 | CES2 (0.52) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7041079 | 0.84 | ATM (0.54) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| Benzoic Acid SCHEMBL29002950 | 0.84 | RAB9A (0.69) | NPC1POLBRAB9ASMN1; SMN2RXRA | |
| SCHEMBL1104605 | 0.83 | KMT2A (0.61) | RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL30438420 | 0.82 | RXRA (0.51) | NPC1POLBRAB9ASMN1; SMN2RXRA | |
| SCHEMBL9439348 | 0.82 | ALDH1A1 (0.69) | NPC1POLBRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11472200 | 0.82 | ATM (0.66) | NPC1RAB9ASMN1; SMN2ALDH1A1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279206-A | Flavor composition | 弗门尼舍有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-110922810-B | Conductive polymer 3D printing ink and preparation method thereof | 江西科技师范大学 | 2022-04-29 | — | — | CN | claimed |
| CN-110845512-B | Total synthesis method of triterpenoid natural product (+) -Arisugacins F/G | 中国海洋大学 | 2020-09-18 | — | — | CN | claimed |
| CN-110845512-A | Total synthesis method of triterpenoid natural product (+) -Arisugacins F/G | 中国海洋大学 | 2020-02-28 | — | — | CN | claimed |
| EP-0358574-B1 | PROCESS FOR THE PREPARATION OF ADAMANTANE-1 DERIVATIVES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1993-02-17 | — | — | EP | claimed |
| US-20240329525-A1 | PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR MANUFACTURING CURED RELIEF PATTERN, AND SEMICONDUCTOR APPARATUS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2024-10-03 | — | — | US | disclosed |
| US-20240210827-A1 | PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR MANUFACTURING CURED RELIEF PATTERN, AND SEMICONDUCTOR APPARATUS | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2024-06-27 | — | — | US | disclosed |
| CN-113666826-B | Aryl or heteroaryl methoxylation reaction method | 五邑大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-117736097-A | Method for preparing carboxylic ester compound by oxidative cleavage of carbon-carbon double bond of olefin compound | 中国科学院大连化学物理研究所 | 2024-03-22 | — | — | CN | disclosed |
| US-20230373932-A1 | DIHYDROPYRIMIDIN-2-ONE COMPOUNDS AND MEDICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2023-11-23 | — | — | US | disclosed |
| US-11697636-B2 | Substituted benzamides | HOFFMANN-LA ROCHE INC. (US) | 2023-07-11 | — | — | US | disclosed |
| CN-113820920-B | Photosensitive resin composition, method for producing cured relief pattern, and semiconductor device | 旭化成株式会社 | 2023-07-04 | — | — | CN | disclosed |
| US-20030181496-A1 | Pyrrole derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2003-09-25 | — | — | US | disclosed |
| EP-1310485-A1 | PYRROLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2003-05-14 | — | — | EP | disclosed |
| CN-1323309-A | Phenyl xanthine derivatives | GLAXO GROUP LTD (GB) | 2001-11-21 | — | — | CN | disclosed |
| US-5783587-A | PSYCHOLOGICAL AND BRAIN DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-07-21 | — | — | US | disclosed |
| EP-0839134-A1 | BENZOYL PIPERIDINES/PYRROLIDINES FOR ENHANCING SYNAPTIC RESPONSE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-05-06 | — | — | EP | disclosed |
| US-5650409-A | FOR IMPROVING MEMORY, OR TREATING DEPRESSION, ALCOHOLISM OR SCHIZOPHRENIA | CORTEX PHARMACEUTICALS, INC. (US) | 1997-07-22 | — | — | US | disclosed |
| WO-1996038414-A1 | BENZOYL PIPERIDINES/PYRROLIDINES FOR ENHANCING SYNAPTIC RESPONSE | CORTEX PHARMACEUTICALS, INC. (US) | 1996-12-05 | — | — | WO | disclosed |
| US-4640906-A | ORGANOALUMINUM COMPOUND, PIPERIDINE DERIVATIVE AND SOLID FROM DIALKOXYMAGNESIUM COMPOUND, AROMATIC DIESTER AND HALOGENATED HYDROCARBON | TOHO TITANIUM CO., LTD. (JP) | 1987-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181496-A1 | Pyrrole derivatives | NCOA1, PKD1, NR3C2 | NPC1 1814/4885POLB 3063/4885RAB9A 2993/4885 |
| US-20230373932-A1 | DIHYDROPYRIMIDIN-2-ONE COMPOUNDS AND MEDICAL USE THEREOF | REN, PKD2, ALPI | NPC1 380/4885POLB 4485/4885RAB9A 1525/4885 |
| US-11697636-B2 | Substituted benzamides | TAAR1, TAAR5, NPY1R | NPC1 937/4885POLB 2718/4885RAB9A 1592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.