Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | EIF4E | P06730 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7640481 | 0.84 | HTR2B (0.47) | RAB9AALDH1A1SMN1; SMN2BCAT2HTT | |
| SCHEMBL7646547 | 0.82 | CA12 (0.42) | MYCBCAT2CA1CA2CA9 | |
| SCHEMBL6913314 | 0.80 | FGFR1 (0.38) | KMT2AALDH1A1SMN1; SMN2BCAT2CA1 | |
| SCHEMBL7641014 | 0.78 | CA12 (0.46) | BCAT2CA1CA2CA9LMNA | |
| SCHEMBL7643298 | 0.73 | ALDH1A1 (0.43) | KMT2AALDH1A1GAASMN1; SMN2CA1 | |
| SCHEMBL27659760 | 0.71 | BCAT2 (0.69) | CYP3A4CYP2C9ALOX12RAB9AKMT2A | |
| SCHEMBL7822299 | 0.71 | BCAT2 (0.69) | CYP3A4CYP2C9ALOX12RAB9AKMT2A | |
| SCHEMBL15559032 | 0.71 | CA1 (0.51) | CYP3A4CYP2C9ALOX12KMT2AALDH1A1 | |
| SCHEMBL6906325 | 0.70 | LMNA (0.44) | PKMRXFP1KMT2AALDH1A1BCAT2 | |
| SCHEMBL36145 | 0.69 | ALDH1A1 (0.72) | CYP3A4CYP2C9ALOX12KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432994-B1 | CARDIOVASCULAR DISORDERS, GLAUCOMA; ANTIINFLAMMATORY, WOUND HEALING, HYPOTENSIVE, ANTIASTHMATIC, AND ANTIANAPHYLACTIC AGENTS | TEXAS BIOTECHNOLOGY CORPORATION | 2002-08-13 | — | — | US | disclosed |