Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646547 | 0.85 | CA12 (0.42) | HTR2BBCAT2HPGDCA2CA12 | |
| SCHEMBL7643245 | 0.84 | CYP3A4 (0.41) | RAB9ABCAT2ALDH1A1MAPTCA2 | |
| SCHEMBL6913314 | 0.83 | FGFR1 (0.38) | HTR2BTHRBBCAT2ALDH1A1MAPT | |
| SCHEMBL7641014 | 0.82 | CA12 (0.46) | HTR2BBCAT2CA2CA12CA1 | |
| SCHEMBL7647137 | 0.82 | IKBKB (0.43) | ALDH1A1HPGDHSD17B10CA2CA12 | |
| SCHEMBL7643298 | 0.76 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDHSD17B10KDM4E | |
| SCHEMBL27634010 | 0.75 | HTR2B (0.39) | HTR2BRAB9ATHRBALDH1A1MAPT | |
| SCHEMBL6909617 | 0.71 | CA2 (0.41) | RAB9AALDH1A1MAPTHPGDHSD17B10 | |
| Urea SCHEMBL28397762 | 0.70 | HPGD (0.54) | HTR2BRAB9ATHRBBCAT2ALDH1A1 | |
| SCHEMBL6906325 | 0.70 | LMNA (0.44) | THRBBCAT2ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432994-B1 | CARDIOVASCULAR DISORDERS, GLAUCOMA; ANTIINFLAMMATORY, WOUND HEALING, HYPOTENSIVE, ANTIASTHMATIC, AND ANTIANAPHYLACTIC AGENTS | TEXAS BIOTECHNOLOGY CORPORATION | 2002-08-13 | — | — | US | disclosed |