Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.36 |
| ▸ | ATP4A | P20648 | 2/20 | 0.36 |
| ▸ | ATP4B | P51164 | 2/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7640481 | 0.85 | HTR2B (0.47) | CA12CA1CA2CA9BCAT2 | |
| SCHEMBL6913314 | 0.83 | FGFR1 (0.38) | CA12CA1CA2CA9TP53 | |
| SCHEMBL7641014 | 0.82 | CA12 (0.46) | CA12CA1CA2CA9BCAT2 | |
| SCHEMBL7647137 | 0.82 | IKBKB (0.43) | CA12CA1CA2CA9SLC9A1 | |
| SCHEMBL7643245 | 0.82 | CYP3A4 (0.41) | CA1CA2CA9BCAT2MYC | |
| SCHEMBL7643298 | 0.77 | ALDH1A1 (0.43) | CA12CA1CA2IKBKBHPGD | |
| SCHEMBL12495840 | 0.72 | BCAT2 (0.62) | SLC9A1ATP4AATP4BIKBKBBCAT2 | |
| SCHEMBL6909617 | 0.71 | CA2 (0.41) | CA12CA1CA2CA9TP53 | |
| SCHEMBL6906325 | 0.71 | LMNA (0.44) | CA2TP53BCAT2POLBHPGD | |
| SCHEMBL27957399 | 0.70 | CA1 (0.50) | CA12CA1CA2CA9TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432994-B1 | CARDIOVASCULAR DISORDERS, GLAUCOMA; ANTIINFLAMMATORY, WOUND HEALING, HYPOTENSIVE, ANTIASTHMATIC, AND ANTIANAPHYLACTIC AGENTS | TEXAS BIOTECHNOLOGY CORPORATION | 2002-08-13 | — | — | US | disclosed |