SCHEMBL764369

SCHEMBL764369

CN1CC(C(=O)c2oc(C(=O)N3CCOCC3)cc2CC2C=CC(F)=CC2)=C(O)C1=O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 5/20 0.33
TSHR P16473 1/20 0.32
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL754228 0.79 LIPG (0.42) LIPGTSHRHSP90AA1
SCHEMBL754205 0.61 LIPG (0.47) LIPGHSP90AA1
SCHEMBL755310 0.61 LIPG (0.43) LIPGHSP90AA1
SCHEMBL27861788 0.60 ALDH1A1 (0.46) TSHR
SCHEMBL756755 0.59 ALDH1A1 (0.47) TSHR
SCHEMBL753861 0.57 LIPG (0.43) LIPGHSP90AA1
SCHEMBL754083 0.57 LIPG (0.45) LIPGHSP90AA1
SCHEMBL14259602 0.55 LIPG (0.47) LIPG
SCHEMBL23815492 0.55 RAB9A (0.48) TSHR
SCHEMBL754256 0.55 LIPG (0.49) LIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1422218-B1 ANTIVIRAL AGENT SHIONOGI & CO (JP) 2012-03-21 EP disclosed