SCHEMBL7644412

SCHEMBL7644412

COc1ccn(C)/c(=N\N)n1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NNMT P40261 1/20 0.32
PDE2A O00408 1/20 0.31
PDE10A Q9Y233 1/20 0.31
BRD9 Q9H8M2 1/20 0.31
BRD7 Q9NPI1 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MTNR1A P48039 1/20 0.30
MTNR1B P49286 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7644422 1.00 NNMT (0.32) NNMTPDE2APDE10ABRD9BRD7
SCHEMBL7646554 0.75 PIK3CB (0.39)
SCHEMBL7646558 0.75 PIK3CB (0.39)
SCHEMBL8710795 0.71 BRD9 (0.40) NNMTPDE2APDE10ABRD9BRD7
SCHEMBL7642369 0.69 LMNA (0.35) L3MBTL1
SCHEMBL7642373 0.69 LMNA (0.35) L3MBTL1
SCHEMBL7641636 0.68 KMT2A (0.47)
SCHEMBL7647192 0.67 SMPD3 (0.42) PDE10A
SCHEMBL22337647 0.65 MTNR1A (0.50) PDE2APDE10ABRD9BRD7MTNR1A
SCHEMBL6691228 0.60 CYP3A4 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002074267-A1 NOVEL DYEING COMPOSITIONS FOR THE DYEING OF KERATIN FIBRES COMPRISING 6-MEMBERED HETEROCYCLIC HYDRAZONE COMPOUNDS AS AN OXIDATION BASE L'OREAL (FR) 2002-09-26 WO disclosed