Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7642369 | 1.00 | LMNA (0.35) | LMNASMN1; SMN2MEN1CYP1A2KMT2A | |
| SCHEMBL7644415 | 0.70 | MAOA (0.33) | — | |
| SCHEMBL7644422 | 0.69 | NNMT (0.32) | L3MBTL1 | |
| SCHEMBL7644412 | 0.69 | NNMT (0.32) | L3MBTL1 | |
| SCHEMBL1758568 | 0.60 | L3MBTL1 (0.34) | LMNASMN1; SMN2MEN1CYP1A2KMT2A | |
| SCHEMBL2984728 | 0.60 | ALDH1A1 (0.44) | SMN1; SMN2MEN1CYP1A2KMT2AALDH1A1 | |
| SCHEMBL4716253 | 0.60 | ALDH1A1 (0.50) | LMNASMN1; SMN2CYP1A2L3MBTL1ALDH1A1 | |
| SCHEMBL9409277 | 0.59 | DYRK1A (0.32) | L3MBTL1ALDH1A1 | |
| SCHEMBL1067804 | 0.58 | LMNA (0.48) | LMNASMN1; SMN2CYP1A2L3MBTL1ALDH1A1 | |
| SCHEMBL151590 | 0.58 | ALDH1A1 (0.59) | LMNASMN1; SMN2CYP1A2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002074267-A1 | NOVEL DYEING COMPOSITIONS FOR THE DYEING OF KERATIN FIBRES COMPRISING 6-MEMBERED HETEROCYCLIC HYDRAZONE COMPOUNDS AS AN OXIDATION BASE | L'OREAL (FR) | 2002-09-26 | — | — | WO | disclosed |