Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17836967 | 0.82 | HTR2A (0.45) | TSHRHTR2AHRH1LMNATAAR1 | |
| SCHEMBL19779659 | 0.81 | TSHR (0.39) | ALDH1A1L3MBTL1HPGDTSHRKDM4E | |
| SCHEMBL20621249 | 0.80 | TSHR (0.43) | ALDH1A1L3MBTL1HPGDTSHRKDM4E | |
| SCHEMBL5801541 | 0.76 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1TSHRKDM4EUSP2 | |
| SCHEMBL19768970 | 0.75 | GABRA1 (0.40) | ALDH1A1L3MBTL1HPGDTSHRLMNA | |
| SCHEMBL28261050 | 0.75 | TSHR (0.48) | ALDH1A1HPGDTSHRKDM4EHSD17B10 | |
| SCHEMBL29184869 | 0.73 | L3MBTL1 (0.37) | ALDH1A1L3MBTL1HPGDTSHRKDM4E | |
| SCHEMBL84270 | 0.73 | TSHR (0.36) | ALDH1A1L3MBTL1HPGDTSHRLMNA | |
| SCHEMBL11205377 | 0.72 | HTR2A (0.54) | TSHRHTR2AHRH1LMNATAAR1 | |
| SCHEMBL11706315 | 0.71 | HTR2A (0.45) | ALDH1A1TSHRMAPTHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263718-A1 | NOVEL USE OF PHENYLHETEROALKYLAMINE DERIVATIVES | AstraZeneca AB (SE) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001062721-A1 | NOVEL USE OF PHENYLHETEROALKYLAMINE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-08-30 | — | — | WO | disclosed |