Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
| ▸ | NQO2 | P16083 | 2/20 | 0.31 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.31 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.31 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7642818 | 0.88 | ALDH1A1 (0.34) | ALDH1A1LMNAMAPK1SMN1; SMN2TRPV1 | |
| SCHEMBL7594183 | 0.84 | HSP90AA1 (0.37) | ALDH1A1LMNAMAPK1SMN1; SMN2HTT | |
| SCHEMBL7599038 | 0.81 | NPC1 (0.37) | ALDH1A1LMNAMAPK1SMN1; SMN2HTT | |
| SCHEMBL7592861 | 0.81 | NPC1 (0.37) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL7594461 | 0.81 | RAB9A (0.40) | ALDH1A1SMN1; SMN2MAPTNQO2CYP19A1 | |
| SCHEMBL7592864 | 0.77 | NQO2 (0.38) | ALDH1A1LMNASMN1; SMN2HSP90AA1MAPT | |
| SCHEMBL7645402 | 0.77 | CYP19A1 (0.34) | LMNAHTTHSP90AA1MAPTRECQL | |
| SCHEMBL6321843 | 0.72 | NPC1 (0.38) | ALDH1A1LMNAMAPK1SMN1; SMN2HTT | |
| SCHEMBL7594464 | 0.72 | NQO2 (0.36) | LMNASMN1; SMN2MAPTNQO2TSHR | |
| SCHEMBL6320203 | 0.69 | RAB9A (0.37) | ALDH1A1LMNASMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850945-B1 | Chiral diphosphine compound, intermediate for preparing the same, transition metal complex having the same diphosphine compound as ligand and asymmetric hydrogenation catalyst | TAKASAGO PERFUMERY CO LTD (JP) | 2002-11-27 | — | — | EP | disclosed |
| EP-0850945-A1 | Chiral diphosphine compound, intermediate for preparing the same, transition metal complex having the same diphosphine compound as ligand and asymmetric hydrogenation catalyst | Takasago International Corporation (JP) | 1998-07-01 | — | — | EP | disclosed |