Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649201 | 0.92 | GRIN1 (0.42) | ALOX15L3MBTL1GRIN1GRIN2BABL1 | |
| SCHEMBL7646145 | 0.84 | MMP8 (0.46) | ALOX15L3MBTL1GRIN1GRIN2BABL1 | |
| SCHEMBL7650967 | 0.80 | THRB (0.43) | S1PR1S1PR3S1PR2S1PR4GABBR2 | |
| SCHEMBL7645204 | 0.79 | RHOC (0.45) | S1PR1S1PR3S1PR2S1PR4GABBR2 | |
| SCHEMBL7648081 | 0.77 | EPHX1 (0.44) | LMNAALOX15GAAL3MBTL1ALDH1A1 | |
| SCHEMBL7646886 | 0.75 | ALDH1A1 (0.55) | S1PR1S1PR3S1PR2S1PR4GABBR2 | |
| SCHEMBL7648476 | 0.73 | MAPT (0.53) | S1PR1S1PR3S1PR2S1PR4GABBR2 | |
| SCHEMBL7650077 | 0.73 | ALDH1A1 (0.59) | S1PR1S1PR3S1PR2S1PR4CYP1A2 | |
| SCHEMBL7646938 | 0.73 | RHOC (0.41) | CYP1A2LMNAALOX15GAAL3MBTL1 | |
| SCHEMBL7649208 | 0.72 | MMP2 (0.42) | S1PR1S1PR3S1PR2S1PR4GABBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100871-A1 | NEW COMPOUNDS USEFUL IN REFLUX DISEASE | ASTRAZENECA AB (SE) | 2002-12-19 | — | — | WO | claimed |
| WO-2002100871-A1 | NEW COMPOUNDS USEFUL IN REFLUX DISEASE | ASTRAZENECA AB (SE) | 2002-12-19 | — | — | WO | disclosed |