Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CDC25A | P30304 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
| ▸ | S100A4 | P26447 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4054488 | 0.97 | MAPT (0.34) | MAPTMITFALDH1A1HTTNPSR1 | |
| SCHEMBL4315247 | 0.97 | MAPT (0.34) | MAPTMITFALDH1A1HTTNPSR1 | |
| SCHEMBL4063433 | 0.91 | MITF (0.31) | MAPTMITFALDH1A1HTTNPSR1 | |
| SCHEMBL5178882 | 0.80 | FABP4 (0.33) | — | |
| SCHEMBL3354011 | 0.79 | S100A4 (0.33) | S100A4 | |
| SCHEMBL4061870 | 0.77 | SLC6A2 (0.32) | — | |
| SCHEMBL1775470 | 0.76 | PDCD1 (0.33) | CYP2A6 | |
| SCHEMBL4275883 | 0.75 | S100A4 (0.33) | S100A4 | |
| SCHEMBL7929749 | 0.73 | PDCD1 (0.32) | MAPTMITFALDH1A1HTTNPSR1 | |
| SCHEMBL7643159 | 0.73 | CYP2D6 (0.33) | S100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0849292-B1 | Olefin polymerisation catalysts and processes for producing olefin polymers | TOSOH CORP (JP) | 2002-08-21 | — | — | EP | disclosed |
| US-6110858-A | AN OLEFIN POLYMERIZATION CATALYST CONSISTS OF A TRANSITION METAL COMPOUND, A MODIFIED CLAY COMPOUND CONTAINING CLAY MINERAL AND AN AMINE COMPOUND AND AN ORGANOALUMINUM COMPOUND | TOSOH CORPORATION (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0849292-A1 | Olefin polymerisation catalysts and processes for producing olefin polymers | TOSOH CORPORATION (JP) | 1998-06-24 | — | — | EP | disclosed |