Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO2 | Q9NYQ3 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 2/20 | 0.42 |
| ▸ | RPA1 | P27694 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5255490 | 0.86 | MAPK14 (0.61) | HAO2MAPK14 | |
| Water SCHEMBL5256024 | 0.84 | MAPK14 (0.59) | HAO2MAPK14 | |
| SCHEMBL3244761 | 0.81 | CA1 (0.51) | CA12MEN1KMT2A | |
| SCHEMBL28180311 | 0.77 | PRKAB2 (0.42) | HAO2DHODH | |
| SCHEMBL16197762 | 0.76 | ALPL (0.46) | MAPK14CA12ALPLTYMP | |
| SCHEMBL4964605 | 0.76 | HAO2 (0.53) | HAO2CA12ALPLRPA1 | |
| SCHEMBL4591235 | 0.74 | GYS1 (0.51) | HAO2CA12ALPLRPA1MEN1 | |
| SCHEMBL27656187 | 0.72 | ALPL (0.43) | CA12ALPL | |
| SCHEMBL8637373 | 0.72 | F10 (0.42) | CA12 | |
| SCHEMBL30078174 | 0.71 | HAO2 (0.55) | HAO2CA12ALPLRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002538142-A | — | — | 2002-11-12 | — | — | JP | claimed |
| EP-1154999-A1 | NITROXYDERIVATIVES HAVING ANTIINFLAMMATORY, ANALGESIC AND ANTITHROMBOTIC ACTIVITY | NICOX S.A. (FR) | 2001-11-21 | — | — | EP | claimed |
| WO-2000051988-A1 | NITROXYDERIVATIVES HAVING ANTIINFLAMMATORY, ANALGESIC AND ANTITHROMBOTIC ACTIVITY | NICOX S.A. (FR) | 2000-09-08 | — | — | WO | claimed |